GI path

Question 1

most common salivary gland tumor type

Answer 1

pleomorphic adenoma

Question 2

most common salivary gland tumor location

Answer 2

parotid

Question 3

most common cancerous salivary gland tumor

Answer 3

mucoepidermoid carcinoma

Question 4

casues achalsia

Answer 4

failure of relaxation of the LES due to loss of myenteric plexus

Question 5

sx of achalasia

Answer 5

progessive dysphasia to solids AND liquids

Question 6

can cause 2ndary achalasia

Answer 6

chagas dx and scleroderma

Question 7

boerhaave syndrome

Answer 7

transmural esophageal rupture due to violent retching

Question 8

can cause esophageal strictures

Answer 8

lye and acid reflux

Question 9

plummer vinson syndrome triad

Answer 9

dysphagia (esophageal webs)
glossitis
iron deficiency anemia

Question 10

early childhood malasborption with neuro sx

Answer 10

abetalipoproteniemia

Question 11

HLA in celiac sprue

Answer 11

HLA DQ2/8

Question 12

extra intestinal manifestations of celiac

Answer 12

dermitidis herptefidormis and T cell lymphoma in skins

Question 13

can cause 2ndary gastricis

Answer 13

burns (curling's)
brain injury (cushing's)

Question 14

ulcer with greater pain after meals

Answer 14

gastric

Question 15

nearly 100% assiciated with H pylori

Answer 15

duodenal ulcer

Question 16

more likely ulcer to perforate

Answer 16

duodenal

Question 17

ulcer on less curvature bleeds from

Answer 17

left gastric artery

Question 18

ulcer on posterior wall of duodenum bleeds from

Answer 18

gastroduodenal artery

Question 19

extraintestinal manifestations of crohn’s

Answer 19

migratory polyartheritis, erythema nodusum, spondy, eveitis, kidney stones

Question 20

extra-intestinal manifesations of ulcerative colitis

Answer 20

pyoderma gangrenosum, andy, uvetits, cholangitis

Question 21

tx for chron’s

Answer 21

immunosuppressents

Question 22

tx for ulcertive colitis

Answer 22

sulfasalazine, 6-MP, infliximab, colectomy

Question 23

colonic polyps more likely to be benign

Answer 23

tubular

Question 24

precancerous polyps

Answer 24

adeomatous

Question 25

ascending colon cancer presentation

Answer 25

iron def anemia, weight loss

Question 26

decending colon cancer presentation

Answer 26

toothpaste stool, bloody stool, colicy pain

Question 27

tumor marker for colorectal cancer recurrence

Answer 27

CEA

Question 28

order of gene events in colon cancer (APC/beta-catenin - most common)

Answer 28

AK-53 (loss of APC --> K-ras mutation --> loss of P53)

Question 29

sx of carcinoid syndome (tumors of neuroendocrine cells outside of GI system)

Answer 29

wheezing, RH heart murmurs, diarrhea, flushing

Question 30

why do neurocrine tumors IN GI not show carcinoid syndrome

Answer 30

liver metabolizes secreted 5-HT

Question 31

elevated ALT > elevated AST

Answer 31

viral hep

Question 32

elevated ATS > ALT

Answer 32

EtHO ism

Question 33

high ALP indicates

Answer 33

obstructive liver dx, bone disease, bile duct dx

Question 34

elevated GGT

Answer 34

liver and biliarydx, but NOT bone dx

Question 35

elevated in acute pancreatitis

Answer 35

lipase (more specific) amylase

Question 36

high a-fetpprotein with liver sx

Answer 36

hepatocarcinoma

Question 37

don't EVER biopsy a

Answer 37

cavernous hemangioma

Question 38

liver can be from OCP or steroids

Answer 38

hepatic adema

Question 39

can caus angiosarcoma

Answer 39

arsenic and PVC

Question 40

occlusion of IVC or hepatic veins with centrilobar congestion and necrosis - leading to congetsive liver dx

Answer 40

Budd-Chiari

Question 41

signs of Budd-Chiari

Answer 41

varices and visibale abdominal and back veins

Question 42

cirrosis and empyshema

Answer 42

a1-antitrypsin deficiency

Question 43

high urine bilirubn/low urine urobilonogen

Answer 43

hepatocellular, or obstructive jaundice

Question 44

no urine bilirubin and high urine urobilinogen

Answer 44

indirect jaundice

Question 45

mild jauncide with stress and fasting

Answer 45

Gilbert's

Question 46

severe earlylife jaundice with bilirubin depo in brain

Answer 46

crigler-najjar syndrome (II is less severe - treat with phenobarbital)

Question 47

causes crigler-najjar syndrome

Answer 47

absent UDP-gluconyl transferase

Question 48

conjugated bilirubin not excreted

Answer 48

dubin-johnson

Question 49

radiolucent gallstones

Answer 49

cholesterol (most common type)

Question 50

obstructive jaundice with palpable nontender gallbladder

Answer 50

Pancreatic cancer (courvoiser's sign)