Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Step 1 - Path > heme > Flashcards

heme Flashcards

1
Q

spur cell RBC

A

liver dx, abetalipoproteinemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

basophilic stippling RBC

A

thalassemias, anemia of chronic dx, lead poisoning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

bite cell RBC

A

G6PD defiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

elliptocyte RBC

A

heriditary elliptocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

macro-ovalocyte RBC

A

megaloblastic anemia, marrow failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

schistocyte, helmet cell

A

DIC, TTP.HUS, traumatic hemolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

spherocyte RBC

A

autoimmune hemolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

teardrop RBC

A

hbone marrow infiltration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

target cell RBC

A

hBC dx, asplenia, liver dx, thalessemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

heinz bodies

A

leads to bite cells, G6PD.a-thalessemia can look like heinz bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

howell-jolly bodies

A

functional hypo/asplenia or naptheline ingestion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

causes of microcytic anemia

A 
iron deficncy
anemia of chronic dx
thalessemias
Pb 
sideroblastic anemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

mauses of normocytic, nonhemolytic anemia

A

ACD
aplastic anemia
chronic kidney dx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

casues of normocytic hemolytic anemoa

A 
hereditary spherocytosis
G6PD def
HbC
sickle cell
paroxymal nocturnal hemoglobinuria
autoimmune
infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

causes of macrocytic magaloblastic anemia

A

folate deficiency
B12 deficency
orotic aciduria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

casues of amcrocytic non-megaloblastic anemia

A

liver dx
EtOHism
reticulolytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

defect in alpha-thalassemia

A

no alpha-globulin (more genes effected, worse outcome - 4 is incompatible w/life)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

B-thalessemia prevelent in

A

med populations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

alpha thalesemia prevelent in

A

cis-asian

trans - afrrican

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

crew-cut skull x-ray and chipmunk facies

A

B thalissema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

sx of Pb poisoning

A

lines on ginginvae and on metaphysis of long bones
encephalopathy and erythrocyte basophilic stippline
sideroblastic anemia
wrist and foot drop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

tx for lead poisoning

A

dimercaprol, EDTA

succimer for chelation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

cause of sideroblastic anemia

A

hereditary - X linked defect in ALA synthase gene

reversible - alchohol, lead and isonizad

24
Q

tx for sideroblastic anemia

A

B6

25
Q

lab diff between B6 and B12 def

A

B12 gas high methylmalonic acid (and neuro sx)

26
Q

can cause folate def

A

malnutrition

27
Q

tracts that B12 def impacts

A

posterior columns

lateral corticospinal

28
Q

megaloblastic anemia that cannot be cured with B6/B12

A

orotic anemia

29
Q

tx for orotic anemia

A

uridine monophosphatase

30
Q

signs of intravascular hemolysis

A

low haptoglobin, high LDH, hemoglobin in urine,

31
Q

signs of extravascular hemolysis

A

high LDH/unconj bili

32
Q

can cause aplastic anemia

A

radiation, benzene, chloramphenicol, alkalyting agents, antimetabolites
B19, EBV, HIV, HCV
acute hep

33
Q

hemolytic anemia in newborn

A

pyruvate kinase deficiency

34
Q

impaird synth of GPI anchor on RBC membrane

A

parox nocturnal hemoglobinuria

35
Q

spleen effect in sickle cell

A

autosplenectomy

36
Q

chronic cnemia seen in SLE, CLL and a-methyldopa

A

warm (IgG agglutinin) autoinmmune hemolytic anemia

37
Q

chronic anemia in a cold, CLL, mycoplasma, and mono

A

cold (IgM agglutinin) autoinmmune hemolytic anemia

38
Q

RLS in heme formation

A

glycine+ succinyl CoA + B6 into g-aminovulvenic acid

39
Q

most common porphyria

A

cutanea tarda

40
Q

sx of acute intermittend porphyria

A

painful abdomen
port-wine urine
polyneuropathy
psych disturbances

41
Q

normal PT and prolonged PTT

A

hemophilia A/B

42
Q

prolonged PT and PTT

A

vit K defiency

43
Q

signs of platelet disorders

A

mucous membrane bleeding, epistaxis, petechiae, pupura, longbleeding time, low platelet count

44
Q

defect in platelet plug formation

A

bernard soulier syndrome

45
Q

deficncy of ADAMTS 13

A

Thrombotic thrombocytopenic purpura

46
Q

long bleeding time and possible prolonged PTT

A

vWF deficiency

47
Q

most common inhrited bleeding disorder

A

von willibrands

48
Q

tx for vWF defic

A

DDAVP

49
Q

most common cause of hypercoag in whites

A

factor V leiden

50
Q

venous clots

A

prothrombin gene mutation

51
Q

risk of thrombotic skin necrosis after admin of warfarin

A

protein C or S defic

52
Q

indication for packed RBCs

A

acute blood loss, severe anemia

53
Q

indication for platelets

A

stop significant bleeding

54
Q

indication for fresh frozen plasma

A

DIC, cirrohsis, warfarin OD

55
Q

indication ffor crypreciperate

A

coag factor deficiencies

Step 1 - Path (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions