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Reproduction and sexual health > Reproductive endocrinology > Flashcards

Reproductive endocrinology Flashcards

1
Q

How can you group ovulatory disorders

A

Group 1-3

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2
Q

What is PCOS

A

Polycystic ovarian syndrome

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3
Q

what are the criteria for PCOS

A

2/3 of:
oligo/amenorrhoea
hyperandrogenism - clinical/lab findings
polycystic ovaries on USS

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4
Q

Other features of PCOS

A

Insulin resistance (can lead to increased risk of developing DM)
Impaired glucose tolerance
Insulin lowers levels of SHBG resulting in hyperandrogenism
LH can mimic insulin and there are higher levels of LH than FSH in PCOS
Obesity
Acne
Hirsutism
Acanthosis nigricans

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5
Q

Investigations for PCOS

A

Hormone profile - oestrogen, TFT, androgens, FSH, LH
Blood glucose
UPT
USS

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6
Q

Management of PCOS

A

weight loss
DM control - Metformin, diet
COCP - helps to give withdrawal bleed (as progesterone is deficient and helps to prevent hyperplasia as well as increasing SHBG levels which decrease androgen levels)
ovulation induction - clomifene citrate, tamoxifen, letroxole
diathermy

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Reproduction and sexual health (46 decks)

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