Embryology Flashcards
What is gastrulation
Formation of the germ layers: endoderm, mesoderm and ectoderm
What are the divisions of the mesoderm
Paraxial
Intermediate
Lateral plate
Which mesoderm division forms the urogenital system
intermediate mesoderm
At what week of gestation does sexual differentiation occur
week 7
Where do primordial germ cells come from (PGCs)
yolk sac and go into the developing gonads
what are somatic support cells
formed from proliferating epithelium that envelop the PGCs
what are the types of genital ducts formed
Mesonephric/Wollfian duct
Paramesonephric/Mullerian duct
The mesonephric/wollfian duct develops in females, true or false
FALSE
The paramesonephric/mullerian duct develops in females, true or false
TRUE
Which protein triggers development of male development
SRY male transcription factor from presence of Y chromosome
In males, what do somatic support cells become
Sertoli cells
What do sertoli cells do
secrete AMH
stimulate Leydig cells which release testosterone
What is AMH and what is its function
Anti Mullerian Hormone
causes regression of paramesonephric/Mullerian duct
What does testosterone induce the formation of
Vas deferens, epididymis, seminal vesicles
What does DHT induce the formation of
Male external genitalia and prostate