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Reproduction and sexual health > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

why should women avoid NSAIDs in late pregnancy

A

it closes the ductus arteriosus

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2
Q

why should St John’s Wort be avoided

A

interacts with drugs

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3
Q

in A+E/AMU, what should always be done in women of child bearing age before giving a medication

A

pregnancy test

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4
Q

what doses of folic acid should women be on if they are trying to conceive

A

400 ug - normally

5mg - NTD, DM, AEDs, obese

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5
Q

list some teratogenic drugs

A 
ACEI/ARBs
warfarin 
lithium 
Na valproate
phenytoin 
methotrexate 
retinoids
tetracyclines 
alcohol 
sulphonylureas
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6
Q

which drugs should be avoided in late pregnancy

A

NSAIDs
warfarin
opiates
B blockers

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7
Q

is insulin safe in pregnancy

A

yes

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8
Q

what medications are safe to treat hypertension in pregnancy

A

labetolol
methyldopa
nifedipine

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9
Q

management of UTI/asymptomatic bacteriuria in pregnancy

A

1st/2nd trimester - nitrofurantoin

3rd trimester - trimethoprim

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10
Q

which drugs should not be used if breast feeding

A 
lithium 
BZDs
phenobarbitone
amiodarone 
cytotoxics 
bromocriptane
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11
Q

which pregnant women should take daily aspirin

A

PET
DM
Red pathway
APLS

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12
Q

where are B12 and intrinsic factor absorbed

A

ileum

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13
Q

where is Vit D absorbed

A

interstines

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14
Q

where is folate absorbed

A

duodenum

jejunum

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15
Q

where is Fe absorbed

A

Duodenum

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16
Q

when is anti-D given to pregnant women

A

28 and 34 weeks

17
Q

what are sensitising events in terms of Rh disease

A 
miscarriage >12 weeks 
abdominal trauma 
birth 
TOP
ectopic pregnancy
placental abruption 
foetal death 
external cephalic version
18
Q

what happens if you dont give anti-D to a Rh- woman

A

anti-Rh antibodies will attack the baby’s RBC and cause haemolytic anaemia and cause high levels of bilirubin which is harmful

19
Q

what is AFP

A

Alpha feto protein

produced by embryonic yolk sac and foetal liver

20
Q

what is a Kleihauer yest

A

tests for mixing of maternal and foetal blood to see if more anti-D is required

21
Q

which anti-emetic is safe to use in pregnancy

A

cyclizine

22
Q

how do you treat UTI’s/asymptomatic bacteriuria in pregnancy

A

1st + 2nd trimester - nitrofurantoin

3rd trimester - trimethoprim

Reproduction and sexual health (46 decks)

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