Foetal medicine Flashcards
biochemical markers for trisomies in 1st trimester
PAPP A
hCG
biochemical markers for trisomies in 2nd trimester
inhibin A
oestriol
AFP
hCG
2nd trimester screening tests for all trisomies, true or false
false, only screens for Downs
up to which date can 1st trimester testing be done
14 weeks
invasive prenatal diagnostic tests
CVS ~11-13 wk
amniocentesis >15wk
miscarriage risk in invasive prenatal diagnostic tests
1 in 200
what is NIPT
Non-invasive Prenatal Testing
describe NIPT
detects cff-DNA in maternal plasma
arises from trophoblast
detected at 4-5 weeks
cleared within hours of birth
NIPT is 1st/2nd line screening
2nd line
done if trisomy screening is high risk
Nuchal translucency of more than __mm is indicative of an abnormality
3.5mm
when is the foetal anomaly scan done and how many conditions does it screen for
18-20+6 weeks
11 conditions
What should be asked when you identify a foetal abnormality?
what is the abnormality? is it isolated? is it genetic? due to maternal disease? could it be viral? what is the prognosis?
parovirus B19 can cause foetal anaemia, true or false
true
if you have a growth restricted baby, what doppler studies can you do
Amniotic fluid index
foetal umbilical artery
MCA
ductus venosus
when is MUAD done
at the anomaly scan 20 wk
