Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology for Advanced Practice Nurses > Reproductive > Flashcards

Reproductive Flashcards

1
Q

They primary male androgen

A

testosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Androgens are used to treat

A

disorders in males and females.
Hypogonadism in males
Diseases such as cancer and HIV infection in both sexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Andorgens formualations and drug names

A

Testosterone
Testosterone gel
Transdermal testosterone

Fluoxymesterone (injectable)
Methyltestosterone (injectable)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Anabolic steroids are

A

scheduled drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Anabolic steroids are contraindicated in

A

Male breast cancer or prostate cancer
Pregnancy (category X) and lactation
Transdermal drugs not used in women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Androgen ADR

A

Hepatitis, hepatic neoplasm, cholestatic hepatitis, jaundice, and hepatocellular carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Androgen Men ADR

A

gynecomastia, reduced sperm levels, decreased libido at high levels, depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Androgen ADR women

A

menstrual irregularities, virilization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Biggest ADR for androgen (anobolic sterods)

A

liver issues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Androgen Monitoring

A

Serum testosterone levels, lipids, liver function, complete blood count
Men need prostate-specific antigen and digital prostate examinations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Androden prescribed for

A

Primary hypogonadal males
Hypogonadotropic hypogonadism
Male climacteric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

For men who come in asking to be put on testosterone, what is done first

A

Lifestyle managment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Testosterone indictions that the increased risk

A

of prostate cancer with long-term replacement is not as great as thought (unless already present)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Statin therapy can decrease

A

testosterone on a statistically significant level, but clinically insignificant level

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Androgen hormone inhibitors (anitiandrogen)

Also known as and example

A

5a-reductase inhibitors

Propecia, Proscar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q 
Leuprolide acetate (Lupron)
AKA
A

luteinizing hormone-releasing hormone antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Direct antiandrogens

Inhibit

A

androgen uptake or nuclear binding of androgen at target tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Spironolactone (Aldactone) is a

A

An aldosterone antagonist and inhibitor of 5a-reductase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Big use for antiandrogens is

A

treatment of BPH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Fanastroide is used in smaller doses

A

for balding in men

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Spironolactone is used in

A

PCOS for women when they are thought to have too high of a testosterone level

22
Q

Estrogen examples

A 
Conjugated equine estrogens (Premarin)
Esterified estrogens
Estradiol
Ethinyl estradiol
Phytoestrogens
23
Q

Effects of estrogen in the body are

A

Increases bone density
Results in normal skin and blood vessel structure
Affects lipid levels
Reduces bowel motility
Enhances coagulability of blood
Causes edema because of its action on the renin–angiotension system
Maintains stability of the thermoregulatory center

24
Q

blood clot risk associated with

A

estrogen

25
Q

Estrogen-ONLY (unopposed estrogen) products are contraindicated

A

in women with an intact uterus.

must take estrogen with progestrone

26
Q

Estrogen contraindicated in

A

Pregnancy (unless specialist directed low hormone level)
Breast cancer
Estrogen-dependent neoplasia

27
Q

Do not give estrogen in these four situations

A

Active deep vein thrombosis or pulmonary embolism
History in past year of stroke or myocardial infarction
Liver dysfunction
Smokers

28
Q

Smoking and estrogen can

A

raise risk for blood clots

29
Q

Estrogen use

A

Contraception

Combination of estrogen and progestin

30
Q

Estrogen use of per-postmenopausal stimptoms directions

A

Start on lowest dose.
Do not give unopposed estrogen to women with a uterus.
See Hormone Therapy chapter for full information.

31
Q

relief of peri-and postmenopausaul give

A

lowest dose for shortest duration

32
Q

Estrogen other use

A

Vaginal atrophy and dryness
Vaginal cream, tablets, or ring
Osteoporosis (not for primary treatment use)

33
Q

Antiestrogens

A

Clomiphene
Danazl
Tamoxifen
Raloxifene

34
Q

Clomiphene (clomid)

A

Used to initiate ovulation in normogonadotropic, normoprolactinemic, and anovulatory patients

35
Q

Danazol (Danocrine)

A

Used to treat endometriosis

36
Q

Tamoxifen (Nolvadex)

A

Selective estrogen receptor modulator
Adjuvant therapy for breast cancer in patients with estrogen receptor –positive tumors (helps reduce breast cancer risk and protects bone)

37
Q

Raloxifene (Evista)

A

Selective estrogen receptor modulator (SERM) used for osteoporosis

38
Q

Estrogen agonists/antagonists can be used to treat

A

dyspareunia (painful sex) medications have selective estrogen effects.

39
Q

Estrogen agonists/antagonists can have a possible positive

A

impact on breast cancer risk and

Known uterine lining development, but much less than with estrogen

40
Q

Estrogen agonists/antagonists are helpful for those who

A

cannot take progestins

41
Q

Progesterones examples

A 
Progesterone (Promethrium, Progesterone in Oil, Crinone, Prochieve)
Medroxyprogesterone acetate (Provera, Depo-Provera)
Norethindrone (Aygestin)
Megestrol acetate (Megace)
42
Q

Androgen-derived progestins examples

A

Norethindrone, norethindrone acetate, ethynodiol diacetate, norgestrel, desogestrel, levonorgestrel, and norgestimate
Drospirenone: a progestin developed as a derivative of spironolactone

43
Q

Progesterone precautions and contraindications

A

Thromboembolic disease
Breast cancer
Impaired liver function
Depression
Disorders that worsen with fluid retention
Progesterone: Old pregnancy category D.
Norethindrone acetate: Old pregnancy category X.

44
Q

Progesterones: Adverse Drug Reactions

A 
Irregular bleeding
Amenorrhea
Acne
Injectable and implanted progesterone
Weight gain
Irregular menstrual bleeding
Osteoporosis risk with 2+ year use
45
Q

Progesterone only comes with a lot of

A

a lot of fluid retention. Will see bloating.

46
Q

progsterone is not recommended

A

in pregnancy. D or X

47
Q

Postmenopausal hormone replacement

Combined with estrogen when

A

uterus is intact

48
Q

Depo-preva (progestin only)

A

in young women use with caution and try to avoid (up to age 25) because it can cause risk of osteoporosis. It also comes with a 15 lbs weight gain

49
Q

Progesterone use

A

Postmenopausal hormone replacement
Combined with estrogen when uterus is intact
Progestin-only contraception
Progestin-only pills (norethindrone)
Medroxyprogesterone acetate (Depo-Provera)
Progestin implanted intrauterine device (Mirena)

50
Q

Progesterone monitoring

A

Depression
Increased risk of seizures
In diabetes, monitoring of blood glucose

Pharmacology for Advanced Practice Nurses (50 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions