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Pharmacology for Advanced Practice Nurses > Psych Deck 2 > Flashcards

Psych Deck 2 Flashcards

1
Q

Stimulants are the most

A

typically prescribed drugs for the treatment of ADHD

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2
Q

Stimulant MOA

A

block reuptake of NE and DA

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3
Q

Stimulant Adverse Effects

A

Activating/Agitating
– Cardiac issues
– Appetite Suppressant

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4
Q

Stimulant formulations can be

A

short acting or extended release

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5
Q

Risks for stimulatns

A

misuse/abuse

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6
Q

stimulants are also used for

A

narcolepsy, neurobehavioral symptoms after TBI, Elderly for fatigue like depression, weight loss, cognitive impairment who have HIV infection

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7
Q

Stimulants’ are

A

controlled substances

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8
Q

stimulants do what

A

increase motor active, focus, attention, and elevation of the persons food.

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9
Q

simulant side effects

A

irritability, insomnia, dizznies, palpatations, euphoria, weight loss, sudden death, depdendece and psychosis.

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10
Q

stimulant contraindications

A

diabetes, hyperthyroidism, hypertension, issues with aggression, bipolar disorder, psychosis, terets disoroder

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11
Q

Ticks

A

can be unmasked by stimulant disorders

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12
Q

If you have been on a stimulant for a long time

A

do not abruptly stop or you will experience withdrawal

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13
Q

Stimulant two types

A

Methylphenidate Products

Amphetamine Salt Products

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14
Q

Methylphenidate (d) Formulations examples

A

Focalin, Focalin XR

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15
Q

Methylphenidate (d,l) Formulations examples

A

Ritalin IR and ER, Metadate,
Concerta, QuilliChew, Aptensio,
Quillivant, Daytrana, etc.

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16
Q

Amphetamine Mixed Salts (d,l)

Formulations

A

Adderall IR and XR, Adzenys XR

ODT, Mydayis, Dyanavel XR

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17
Q

Dextroamphetamine (d)

Formulations (amphetamine salt)

A

Dexedrine, ProCentra, Zenzedi

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18
Q

Lisdexamfetamine (amphetamine salt)

A

Vyvanse

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19
Q

the d-isomer is more potent for

A

dopamine
transporter (DAT) binding, both d- and l- isomers
are equally potent for NE (NET) transporter
binding.

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20
Q

d-amphetamine will have more action on

A

DAT

than NET

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21
Q

Mood stabilizer drug class

A

Lithium
– Antiseizure Drugs
– Atypical Antipsychotics

22
Q

mood stabilizers used in

A

bipolar disorder, impulsivity, aggression, depression, anxiety, mood liability, chronic pain, pszhoeffecive disorder

23
Q

gold standard for bipolar

24
Q

lithium long term use can

A

damage thyroid and kidneys

25
Q

lithium MOA

A 
Competes with sodium to enter
cell- acts like sodium in the body
• Cholinergic and GABA activity,
dopamine receptor sensitivity,
serotonergic activity, inhibits
second messenger system
26
Q

lithium blood levels

A

Blood levels: 0.6-1.5 mEq/L

27
Q

lithium baseline labs

A

levels of renal, cardiac,

thyroid, and electrolytes.

28
Q

Lithium can lead to

A

neuroprotective actions and

long-term plasticity in the brain

29
Q

Monitor what with lithium

A

sodium levels, when
sodium is lost (dehydration,
excessive sweating, etc.)

30
Q

lithium toxicity S/S

A

(ataxia, slurred
speech, tremor, N/V, tinnitus,
blurred vision)

31
Q

Lithium overdose treated with

A

hemodialysis and supportive

care.

32
Q

Lithium levels above ___ cause ___

A

Levels above 2.5 mEq/L can

cause coma, seizure, and death.

33
Q

Things that effect lithium level

A

dehydration, excessive sweating, illness, AKI. Anything that effects fluid an electrolyte imbalance.

34
Q

If there is a change in a lithium level we want to know

A

what caused that change

35
Q

Lithium is excreated through

A

the kidneys

36
Q

Lithium can lead to

A

long term palcicity and protective actions in the brain when treated early.

37
Q

Lithium patient education

A

limit ETOH and caffene, avoid tasks requirein coodination, may cause dry mouth, maintain steady salt, fluid intake, report vomiting, diarrhea, muscle weakness, tremors, drowsiness, ataxia, monitor levels

38
Q

Aticonvulsants

A

Carbamazepines
– Drugs that affect GABA: gabapentin, topiramate, lamotrigine
– Valproic Acid

REVIEW THESE FROM MODULE FOUR

39
Q

First line treatment for anxiety and second line

A

CBT then antidepressants

40
Q

Benzodiazepines work by

A

increasing GABA

41
Q

Benzodiazepines work

A

really well for anxiety

42
Q

You can ____ from benzo withdrawal

43
Q

Benzodiazapines ADR

A

withdrawal, dizziness, fall risk in elderly, cognitive effects long term

44
Q

serotonergic Anxiolytic example

45
Q

Buspirone works by

A

increasing serotonin

46
Q

buspirone is used on

A

a daily prescirbed basis as an adjuct to an SSRI

47
Q

Barbituates

A

short and log acting formulations. Work on GABA in a different way than benzo, CNS depressants. Risk for tolerance, dependence and overdose.

48
Q

Sedative hypnotics

A

Nonbenzodiazepine Hypnotic

49
Q

GABA non-benzodiazepine receptor examples

A

(zolpidem (Ambien), zaleplon (Sonata),

eszopiclone (Lunesta)

50
Q

melatonin receptor agonist example

A

(ramelteon

Rozerum

51
Q

Orexin receptor antagonist example

A

Orexin receptor antagonist

Pharmacology for Advanced Practice Nurses (50 decks)

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