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Pharmacology for Advanced Practice Nurses > Integumentary System > Flashcards

Integumentary System Flashcards

1
Q

Classification of Skin Disorders - Infections

A

bacterial, fungal, parasitic, viral

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2
Q

Skin disorders - Inflammatory

A

injury and excessive sun
exposure, acne, rosacea, atopic
dermatitis, contact dermatitis, seborrheic
dermatitis, stasis dermatitis, psoriasis

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3
Q

Skin disorders - Neoplastic

A

skin cancers, benign neoplasms

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4
Q

Bacterial we use

A

topical, oral, IV

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5
Q

fungal we use

A

topical and oral

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6
Q

viral can be

A

self-limiting

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7
Q

Skin parasites include

A

mites and lice

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8
Q

scabicides kill what

A

kill mites

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9
Q

pediculicids kill what

A

lice

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10
Q

Bacterial skin examples

A

cellulites, impetigo, staff

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11
Q

viral skin examples

A

shingles, warts, herpes

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12
Q

Antibacterial Most common pathogens:

A

staphylococcus and streptococcus

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13
Q

impetigo treated

A

topically unless severe

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14
Q

Systemic antibiotics are required for (5 items)

A 
– Moderate to severe impetigo
– Boils or abscesses
– Perianal strep
– Cellulitis
– Methicillin-resistant Staphylococcus aureus
(MRSA): suspected skin infection
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15
Q

Mupirocin (topical)

A

bactroban, centany. Three times a day for 5 to 14 days

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16
Q

Retapamulin (alatabax)

A

BID for 5 days

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17
Q

Bacitracin

A

2 to 5 times a day until clear

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18
Q

double antibiotic includes

A

bacitracin and polymixin b

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19
Q

tripple antibiotic inclucds

A

bacitracin,

neomycin, and polymixin B

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20
Q

Topical antibacterial monitoring and patient education

A 
Monitoring
– No specific monitoring
• Patient education
– Administration
– Adverse drug reactions
(ADRs)
21
Q

Topical antibacterial lifestyle managment

A 
Lifestyle management
• Perform hand washing
• Do not share towels or
utensils.
• Wash with antibacterial
soap
22
Q

Topical antifungals are used to treat

A

superficial fungal infections

23
Q

examples of topical anitfungals

A 
– Azoles
– Allylamines: naftifine
– Benzylamine: butenafine
– Ciclopirox olamine
– Tolnaftate
– Nystatin
24
Q

Topical Antifungals considerations

A

Few contraindications because of
minimal absorption
– Most are pregnancy category B

25
Q

Systemic antifungal considerations

A

All should be used cautiously in
patients with liver problems.
– Griseofulvin has possible cross- sensitivity with penicillin.

26
Q

Topical antifungals ADR

A

ADRs: Skin irritation, itching, burning, rash
– Gentian violet: may cause staining of skin and
clothing

27
Q

Topical antifungal drug interactions

A

Few interactions

28
Q

Theoretical interaction with

A

azoles and

amphotericin B

29
Q

Clotrimazole intravaginal preparations:
should not be administered
concurrently with

A

nonoxynol-9 and

octoxynol

30
Q

Systemic antifungals: have

A

several

interactions

31
Q

Topical retinoids reduce

A

cohesion between keratinized cells

32
Q

topical antibiotids example for acne

A

benzoyl peroxide - keratoytic effect

33
Q

Systemic Retinoids considerations

A

Systemic Retinoids
– pregnancy category X, cheilitis,
hypertriglyceridemia, CNS effects

34
Q

Acne is classified as

A

mild, moderate and severe

35
Q

mild and moderate acne is treated with

A

topical

36
Q

systemic reinoids used for

A

moderate to severe, nodular cystic acne

37
Q

hypertriglyceridemia can occur in

A

45% of patients

38
Q

oral contraception is used to treat what sometimes

A

acne

39
Q

Topical corticosteroids

A

use the lowest does possible for the shortest amount of time

40
Q

Topical corticosteroids do not

A

abruptly discontinue that are high potency

41
Q

Topical corticosteroids classes

A

1 through 7. One is the most potent and seven is the least potent.

42
Q

Topical Corticosteroids has

A

Nonspecific anti-inflammatory effects

43
Q

Topical Corticosteroids absorption

A

Absorption varies by drug and vehicle
used
– Ointments: more occlusive, so more potent
– Creams: less occlusive, so less potent
– Lotions: least potent
– High dose or over large areas may cause
systemic steroid effects

44
Q

Smooth nonhairy skin, thick, hperteratotic leasions

A

Ointment +++
Cream ++
Foam++

45
Q

Hairy Areas

A

Solution +++
Foam +++
Gel ++
Lotion ++

46
Q

Palms, soles

A

Ointment +++
cream ++
Foam ++

47
Q

Infected areas

A

Solution +++
Foam ++
Lotion ++

48
Q

Between skin folds; moist, macerated lesions

A

cream ++
lotion ++
solution ++
foam ++

Pharmacology for Advanced Practice Nurses (50 decks)

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