Reproduction - Male and Female Flashcards
Bertazzolo et al. Cytologic features and diagnostic accuracy of analysis of effusion for detection of ovarian carcinoma in dogs
Abdomnial effusion is common presenting sign for ovarian carcinoma in dogs
Individual cells were 30 um in diameter, mild anisocytosis and anisokaryosis, moderate pale blue cytoplasm, round to oval paracentral nuclei with fine chromatin and poorly distinct small nucleoli
Sensitivy 86% and 100% and speceificity 57% and 97% for 2 pathologists
Accuracy 98.8% and 93.9%
Brown et al. Fibroepithelial polyps of the vagina in Bitches: a histological and immunohistochemical study
Microscopic features were abundant edematous or fibrous stroma containing spindle-shaped and stellate cells and presence of variable inflammation and hemorrhage
Connective tissue expressed vimentin and desmin, but not SMA or calponin
Individual cases had additional changes such as granulomatous inflammation, epithelial dysplasia suggestive of pappilomavirus infection and lesions resemblinf phyllodes tumor in women
Nelissen et al. Subtotal vaginectomy for management of extensive vaginal disease in 11 dogs
5 dogs had benign vaginal disease and 6 had malignant vaginal neoplasia
No major complications and clinical signs resolved by 4 weeks
1 dog developed metastatic disease and 1 dogs developed PO urinary incontinence
Patsikas et al. Radiographic and ultrasonographic findings of uterine neoplasms in 9 dogs
Radiography revealed soft-tissue opacity between bladder and colon in 6/7 dogs with uterine body/cervival tumors, soft tissue mass in mid-ventral abdomen in 2 dogs with uterine horn tumors
US revealed massses in all dogs with uterine body/cervical tumors and could delineate the origin of the mass in 1/2 dogs with uterine horn tumors
Solid in 3 dogs (leiomyoma), solid and cystic in 4 dogs (2 ACA, 1 leiomyoma, 1 fibroleiomyoma), and cystic in 2 (leiomyomas)
No possoble to ascertain sonographically that mass originated in uterine horn unless there was uterine horn that could be traced
Biopsies needed to diagnose
Saraiva et el. 2015. An immunohistochemical study of sex steroid receptors, Ki67 and cytokeratin 7 and 20 in feline endometrial adenocarcinomas
FEA had downregulation of ER-a and less of PR
FEA retains CK7 and CK20 as evidenced in normal endometrial epithelial, but a decrease in CK7 expression was observed
Holst et al. Anti-Mullerian hormone: a potentially useful biomarker for the diagnosis of canine Sertoli cell tumors
Blood collected from 20 dogs with palpable testicular tumors and 27 healthy controls
Serum analyzed for estradiol-17B and AMH
Control dogs had AMH <10 ng/mL
6 dogs with SCT or mixed tumors containing SCT had AMH >22 ng/mL
Concentrations between 10-22 ng/mL was found in 1/2 dogs with non-neoplastic testicular pathologies or testicular tumors other than SCT
AMH is a promising biomarker for diagnosis of SCT
Banco et al. Immunohistochemical evaluation of the expression of anti-mulleran hormone in mature, immature and neoplastic canine sertoli cells
All SCT expressed AMH - useful marker of immature and neoplastic canine SCs
Banco et al. Immunohistochemical study of mized germ cell sex cord stromal tumors (MGSCT) in 13 canine testes
MGSCTs composed of semineferoud tubules filled with admized neoplastic serrtoli cells and germ cells
Hohsteter et al. Canine testicular tumors: two types of seminomas can be differentiated by IHC
Testicular tumors are the most common genital neoplasm - LCT, SEM, SCT most common forms
Testicular tumors were found in 46% of dogs at necropsy and 7% of tumor biopsied
Median age 10 years
Most common tumor in decreasing order: LCT, mixed tumors, SEM, SCT
