Other Bone Tumors Flashcards
Roynard et al. 2016. MRI treatment and outcome of canine vertebral chrondrosarcomas. Six cases.
Lobulated masses involving the dorsal vertebral compartment, marked hyperintense with few foci of hypointensitiy on T2W, iso- to hypointense of T1W with contrast enhancement
Intralesional surgical resection in 3 dogs and medical management in 1, 2 euthanized
Low tumor grade histologically
Rapid clinical improvement after surgery but 2/3 had local regrowth
CSA locally aggressive and resisatnt to RT and chemotherapy, prognosis depends on en bloc resection
Vinayak et al. 2017. Dedifferentiated chondrosarcoma in the dog and cat: a case series and review of literature
7 dogs and 1 cat
Poor long term survival and high metastatic rate to lungs
Radiographs, CT, MRI - bimorphic pattern consisting of mineralized and nonmineralized areas
Trost et al. 2014. Occurrence of tumors metastatic to bones and multicentric tumors with skeletal involvement in dogs
More ___ dogs presented with bony metastases
The ____ was the primary site of metastatic bone lesions, followed by ___ and ___
__% were gross visible and present in ___ bone
In ___%, metastases could only be diagnosed at microscopic level
Most frquent affected bone?
Female - when mammary tumors were removed gender distribution was equivalent
mammary glands, musculoskletal system, respiratory system
77%, multiple
Vertebrae and humerus
Charney et al. 2017. Skeletal metastasis of canine urothelial carcinoma: pathologic and CT features
9% had confirmed metastases to the vertebrae
21 dogs with UC underwent CT at euthanasia - skeletal lesions detected in 4 dogs and confirmed histologically in 14%
In the 3 cases, mets were suspected based on history and PE, in 1 dog it was unsuspected location
CT can be helpful in detecting skeletal metastases as cause of bone pain as well as identifying clinically “silent” sites of skeletal metastasis
Linderman et al. Feline exocrine pancreatic carcinoma: a retrospective study of 34 cases
Most common clinical signs?
Metastatic disease?
MST?
MST for patients that got chemotherapy and surgery?
Survival with abdominal effusion?
Cats that received NSAID and median survival?
EPC is an aggresssive tumor with high metastatic rate and poor prognosis
Weight loss, decreased appetite, vomiting, palpable abdominal mass, diarrhea
11 cats (32%)
97 days (3 mo)
165 days (5.5 mo)
30 days
26 days
Nicoletti et al. 2018. Postsurgical outcome in cats with exocrine pancreatic carcinoma: 9 cases
Outcome in cats undergoing surgical revomal of the mass
Median post-surgical survival time?
Surgical removal of tumor with localized disease can result in survival times over 300 days
316.5 days, 3 cats alive at median follow up at 309 days
