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Pharmacology 2 > Reproduction > Flashcards

Reproduction Flashcards

1
Q

Which drug is used to treat premature labor in mares?

A

Altrenogest

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1
Q

What are clinical uses for prolactin inhibitors?

A

Mismating in the bitch and queen Pseudopregnancy in the bitch or queen

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1
Q

What is used to treat aglactica?

A

Dopamine antagonists - phenothiazines, metoclopramide, domperidone

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1
Q

What class of drugs is used to treat pituitary dwarfism in dogs?

A

Somatotropin

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2
Q

Treatment of benign prostate hypertrophy in dogs?

A

Castration

Megesterol acetate (inhibits gonadotropins)

Finasteride (inhibits 5 a-reductase)

GnRH antagonists

Large doses of GnRH agonists

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3
Q

What are the major side effects of progestin use?

A

CEH (cystic endometrial hyperplasia) Pyometra

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3
Q

What drug is used to induce abortion in cattle from day 7-150?

A

Prostaglandins

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4
Q

Synchronization of estrus in cattle and controlling the time of estrus in mares?

A

Prostaglandins

Progestins

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4
Q

T/F: There is no treatment for pseudopregnancy in the bitch.

A

True

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5
Q

Progestin approved in bitches?

A

Megestrol acetate

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5
Q

What is the DOC for induction of parturition in cattle in the last month of pregnancy?

A

Dexamethasone

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6
Q

Increasing luteal formation in large animals?

A

GnRH

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6
Q

What drugs are prolactin inhibitors?

A

Bromocriptine

Cabergoline

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6
Q

What drug is used for chemical castration in dogs?

A

Zinc glutonate neutralized with arginine by injection (3-10 months of age)

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7
Q

What are our androgen drugs?

A

Testosterone esters Trenbolone Mibolerone

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9
Q

Diagnosis of LH and testosterone deficiency in small animals?

A

GnRH

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9
Q

What drug is used to stimulate uterine contraction?

A

PGF2a
Estrogens
Oxytocin

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10
Q

What effect to prostaglandins have on the corpus luteum?

A

Regression of the CL by increased intracellular free calcium

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10
Q

Term to describe mismating in large animals?

A

Abortifacient

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11
Q

What are the uterine stimulants?

A

Estrogens Oxytocin PGF2a Glucocorticoids Ergonovine

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11
Q

What drugs cause ejaculation in stallions?

A

Imipramine Xylazine (a2 agonist) PGF2a

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12
Q

Term to describe induction of parturition?

A

Ecbolic (oxytocic)

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12
Q

What is the DOC to induce parturition in the bitch and mare?

A

Oxytocin

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13
Q

What estrogen is used on its own for growth promotion in cattle and sheep?

A

Zeranol

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14
Q

What drug is combined with a progestin for estrus synchronization in cattle?

A

Estradiol valerate

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16
Q

Treatment of cryptorchidism in dogs?

A

hCG

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17
Q

Which drugs are used for contraception and suppression of estrus in small animals?

A

Megestrol acetate in bitches and queens

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18
Q

Administration of what drug before prostaglandins will reduce side effects in small animals?

A

Atropine

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19
Q

What drug should be used to induce abortion in the last month of pregnancy in cattle?

A

Dexamethasone or PGF2a

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21
Q

What drugs can be used as implants in feedlot heifers and steers?

A

Testosterone-estradiol Trenbolone

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21
Q

What are our anabolic steroids?

A

Stanozolol Boldenone

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22
Q

What species is Stanozolol approved in?

A

Dogs, cats, horses

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23
Q

Stimulation of testosterone secretion in large animals?

A

hCG

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23
Q

Androgen antagonists in prostate hypertrophy and tumors, and anal adenoma?

A

Estrogens

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23
Q

Treatment of silent estrus and pyometra in cattle?

A

Prostaglandin

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23
Q

Term to describe mismating in small animals?

A

Antinidatory

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23
Q

Androgens or estrogens used for pseudopregnancy in the bitch?

A

Testosterone cypionate Mibolerone DES

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24
Q

Class of drugs used to maintain pregnancy and promote estrus?

A

Progesterones

25
Q

What class of drugs increase milk production and enhance growth in large animals?

A

Somatotropin

26
Q

What are the adverse effects of prostaglandins in horses?

A

Sweating and colic

27
Q

DOC to expel mummified fetuses in large animals?

A

Prostaglandins

28
Q

Induction of parturition in swine and cattle?

A

Prostaglandins

29
Q

What drug is used to decrease serum progesterone?

A

PGF2a

31
Q

Progestin approved in cattle?

A

Melengestrol acetate

32
Q

Drug used to suppress estrus and synchronization of estrous cycle?

A

Progesterone CIDR in cattle Altrenogest in mares Norgestomet implants and norgestomet-estradiol valerate injection in beef cattle and non-lactating heifers

33
Q

T/F: and ovarian historectomy should be performed during clinical signs of pseudopregnancy.

A

False

35
Q

Induction of ovulation in the mare?

A

hCG GnRH - specifically Deslorelin acetate

36
Q

Treatment of pyometra in large animals with antibiotics?

A

Prostaglandins

38
Q

What drug is used to produce a teaser to identify cows in estrus?

A

Testosterone

39
Q

Induction of ovulation in cats?

A

hCG

41
Q

Progestin approved in cats?

A

Hydroxyprogesterone caproate

42
Q

What class of drugs inhibit uterine contraction?

A

Tocolytics

43
Q

What synthetic prostaglandins are approved in mares?

A

Fluprostenol

44
Q

What drug is used in combination with progesterone or testosterone for growth in cattle?

A

Estradiol

45
Q

DOC for endophyte-induced agalactia in mares?

A

Domperidone

47
Q

Adverse effect of using estrogens in mismating in small animals?

A

Pyometra

49
Q

Prostaglandins have no side effects in what two species?

A

Swine Cattle

49
Q

Induction of parturition in sows?

A

PGF2a alone or with Oxytocin

50
Q

What drugs are listed under tocolytics?

A

Beta 2 agonists (terbutaline, ritodrine) Magnesium sulfate Inhalation anesthetics

51
Q

Induction of parturition in cattle?

A

Glucocorticoids PGF2a

53
Q

What do prostaglandins activate?

A

Protein kinase C

55
Q

Stimulation of follicular growth in anestrous animals

A

eCG

57
Q

Induction of estrus in the bitch?

A

Estrogens

57
Q

During the first 150 days of gestation, what should be used to induce abortion in cattle?

A

PGF2a or its analogs

58
Q

What drugs can be used to treat pseudopregnancy in the bitch?

A

Mibolerone Testosterone

60
Q

Treatment of mismating in dogs and cats?

A

Estrogens (not recommended - can cause pyometra)

62
Q

What is our mycotoxin estrogen?

A

Zeranol

63
Q

What is one of the most common reproductive problems during diestrus in the bitch?

A

Pseudopregnancy

65
Q

What species are PGF2a tham salt and dinoprost trimethamine approved in?

A

Cattle Mares Sows

67
Q

Treatment of mismating in the bitch?

A

Prostaglandins

68
Q

Treatment of urinary incontinence, dermatitis, and vaginitis in the ovarectomized bitch and queen?

A

Estrogens

69
Q

Dopamine agonists used for pseudopregnancy in the bitch?

A

Bromocriptine
Cabergoline
A.K.A. Prolactin inhibitors

70
Q

What synthetic prostaglandins are approved in cattle?

A

Cloprostenol Fenprostalene

71
Q

What drug should be used to induce abortion at 5-8 months gestation in cattle?

A

Combination of PGF2a and dexamethasone

73
Q

Induction of estrus in prepubertal gilts?

A

eCG in combination with hCG

74
Q

Induction of super ovulation in cattle?

A

eCG in combo with PGF2a

75
Q

Increasing libido in male dogs and cats?

A

GnRH

76
Q

What is the most serious reproductive problem in the bitch?

A

CEH

77
Q

Induction of parturition in small animals?

A

Oxytocin

78
Q

What class of drugs is used to treat GH-responsive dermatosis in small animals?

A

Somatotropin

80
Q

Treatment of follicular cysts in cattle?

A

Human chorionic gonadotropin (hCG) GnRH

81
Q

What species is Boldenone approved in?

A

Horses

82
Q

Treatment of follicular cysts in the bitch?

A

hCG GnRH

83
Q

Drugs used as growth promoters in cattle?

A

Progesterone-estradiol benzoate Melengesterol

84
Q

Progestin approved in mares?

A

Altrenogest

85
Q

Progestin approved in beef cattle and non lactating heifers?

A

Norgestomet implants and norgestomet-estradiol valerate injection Syncro Mate B

86
Q

What is our synthetic non steroidal estrogen?

A

DES

88
Q

What are our Estradiol esters?

A

Cypionate Propionate Benzoate Velerate

89
Q

What do prostaglandins inhibit?

A

Steroid synthesis

90
Q

Induction of parturition in the mare?

A

Oxytocin

91
Q

Treatment of uterine infections in the bitch or queen?

A

Prostaglandins

92
Q

Which prolactin inhibitor is better?

A

Cabergoline

93
Q

Which drugs are used to treat behavioral problems and urination in male cats?

A

Hydroxyprogesterone caproate Medroxyprogesterone acetate

94
Q

What drugs can be used to treat suppression estrus in dogs?

A

Milbolerone Testosterone

Pharmacology 2 (13 decks)

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