Repro 4 Flashcards

1
Q

how many couples in the uk require ix for infertility

A

1/6

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2
Q

assess ovarian reserve

A

antral follicle count

AMH

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3
Q

coasting is what

A

treatment for OHSS

stop gonadotrophins

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4
Q

success rate for IVF

A

35%

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5
Q

1s trim ends
2nd trim ends
3rd trim ends

A

12 weeks
28 weeks
40 weeks

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6
Q

complete mole has how much of a risk for becoming choriocarcinoma

A

2.5%

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7
Q

lactobacillus sp in healthy vagina

what does it produce and why

A

lactic acid +/- hydrogen peroxide

suppress growth of other bacteria

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8
Q

tayside syphylis screening

if pos

A

IgG and IgM

if positive then VDRL and TPPA and IgM ELISA fro HIV as well

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9
Q

episode of PID can what

A

increase the risk of chlamydia by 10

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10
Q

increase in maternal age can increase the risk of the baby having what

A

downs

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11
Q

most common cancer in women under 35

A

cervical cancer

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12
Q

do people who have had the HPV vaccine still need to go for smears and why

A

y

HPV vaccine doesn’t protect against 30% cevical cancers

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13
Q

primary action of depo

A

inhibits ovulation

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14
Q

primary action of IUD

A

prevention of fertilisation

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15
Q

primary action IUS

A

effect on implantation

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16
Q

primary action of implant

A

inhibits ovulation

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17
Q

primary action of CHC

A

inhibits ovulation via the action on the hypo-pit-ovarian axis leading to decreased levels of FSH/LH

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18
Q

migraine with aura increases the risk of what when on the CHC

A

iscaehmic stroke

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19
Q

cocp and risk of cervical cancer

A

increase the risk

but risk reduces to baseline 10y after stopping

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20
Q

primary mechanism for POP

A

thickening of cervical mucous

etonorgestrol - suppresss ovulation in up to 97% of cycles

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21
Q

secondary mechanism of POP

A

supression in over 60% ovulation by levongesterol
decreases endometrial receptivity to blastocyte
decreases cilia activity in the fallopian tubes

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22
Q

monochorionic

A

shared placenta

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23
Q

monozygous

A

same egg

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24
Q

monochorionic and monozygous twins at a high risk of what

A

of preg cx

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25
Q

IUGR

A

<10th centile

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26
Q

commonest cause of iatrogenic prem

A

PET

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27
Q

which htn drugs can be breast fed with

A

all of them in preg

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28
Q

methyldopa

A

alpha agonost

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29
Q

labetalol

A

and and beta antagonist

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30
Q

hydrazine

A

vasodilator

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31
Q

nifedipine

A

CCB

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32
Q

oliguria in how many px after delivery

A

30%

no treatment necessary

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33
Q

risk factors for PET

A

75mg aspirin daily

start before 12 w

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34
Q

chronic essential htn present when

A

at booking or <20w

35
Q

gestation htn dx when

A

new htn >20w with no signify proteinuria

36
Q

<140/90 in preg

<130/90

A

consider reducing dose

reduce dose

37
Q

neonatal hypoglycaemia

A

risk of cerebral palsy

38
Q

polycythaemia

A

risk of IUD

39
Q

preg increases what factors and decreases what

A

increases 7, 8, 9, 10, 12, fibrinogen, increased platelets

decreases in 2 and antithrombin 3

40
Q

is warfarin okay in bf

A

y

41
Q

where is the lamboid sututre

A

near the occipital bone

42
Q

mathew duncan

schultz

A

marginal placental seperation - commonest

separation from central aspect

43
Q

se of oxybutinin

A

dry mouth, constipation, blurred vision, solmenance

44
Q

overflow incontincance stop what

A

antocholinergics

45
Q

uterine descent

A

first degree - in vagina
2nd at interiotus (vaginal orifice)
3rd outside vagina
procidenta

46
Q

examination of the newborn done when

A

at 24 hours (72h?)

47
Q

can heparin cross placenta

A

no its a large molecular weight molecule

48
Q

half the deaths of childhood occur when and why

A

in first year of childs life

strong assoc w preterm delivery and low birth weight

49
Q

interval of <6m between preg can what

A

increase risk for preterm

50
Q

what can overinflation of lungs in a preterm baby do

A

inflam - long term morbidity because they r v fragile

51
Q

x linked DMD chance of child getting it

A

1/4

1/2 if know baby is boy

52
Q

SSRIs can what

A

increase FSH/LH

53
Q

mennorhagia treatment

A

NSAIDs - mefenamic acid
tranexomic acid
progesterone, IUS, ablation, hysterectomy

54
Q

mefenamic acid works how

A

decreases blood supply to uterus

55
Q

tranexamic acid

A

anti fibrinolytic

56
Q

where is AFP made

A

in foetal liver crosses placenta into mums blood

57
Q

what causes a high aFP

A

spina bifida, gastrorchisis

58
Q

ideal site for anti D

A

deltoid muscle

59
Q

when should tamoxifen be stopped

A

3m before preg

60
Q

oxybutinin risk

A

double risk for alzheimers
confusion
dont give to anyone with memory problems

61
Q

how long after a miscarriage can someone start trying to get pregnant again

A

after a period

62
Q

menstruation usually starts when

A

11-15

63
Q

imperforate hymen treatment

cx

A

cruciate incision

can lead to infertility and chronic pelvic pain

64
Q

preterm labour/prom

A

erythromycin 250mg qds for 10d

65
Q

age till u can get IVF

A

42

66
Q

candida ix

A

HVS

67
Q

prostitis is what

A

rare cx of UTI in men

68
Q

what should be checked for as well in prostitis

A

chlamydia and gon in px <35

69
Q

primary sites of infection of gon

A

mucous membrane of urethra
endocervix
rectum
pharynx

70
Q

gon is resistant to what

A

penicillins, tetracyclines, quinolone, most oral cephalosporina

71
Q

commonest bacteria STI

A

chlamydia

72
Q

chlamydia swab

A

VVS

73
Q

commonest viral STI

A

warts HPV

74
Q

non enclosed C corohedral virus contains double stranded DNA

A

HPV

75
Q

frothy discharge and must smell

A

tracho vag

76
Q

hiv infection establishes within

A

3 days

77
Q

ophthalmic screenin why in hiv px

A

CD <50

cytomegalovirus

78
Q

karposkis

A

human herpes virus 8

79
Q

karposkis more common in

A

MSM

80
Q

3rd gen detect what

A

ABs

IgG/IgM

81
Q

DCIS involving lobular

involving skin

A

cancerisation

pagets

82
Q

commonest female cancer

how many will develop

A

breast

1/8

83
Q

ducts ectasia effects what

A

subareaolar ducts