Haem4 Flashcards

1
Q

loss of spectrum in RBC

A

hereditary spherocytosis

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2
Q

increased uric acid in what haem cancer

A

CLL

gout

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3
Q

statins work how

A

inhibit coA-reductase

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4
Q

RBC energy how

A

have no mitochondria

anaerobic glycolysis

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5
Q

MPP go forward how

A

can’t self divide

have to differentiate

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6
Q

where is folate absorbed from and how

A

jejunum by diffusion and actively

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7
Q

vit b12 neuro problems

A

posterior/dorsal column problems
neuropathy
dementia
psychiatric manifestations

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8
Q

mechanical valve

A

microangiopathic haemolytic anaemia

MAHA

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9
Q

bone marrow

thymus

A

bone marrow - b cell maturation

thymus - t cell maturation

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10
Q

CD20

CD3

A

b cell marker

t cell marker

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11
Q

in nodules

between them

A

b cells in

t cell between

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12
Q

white pulp

red pulp

A

CD4

CD8

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13
Q

holotransferrin

A

iron and transferrin

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14
Q

apotransferrrin

A

no iron

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15
Q

ferratin

A

acute phase protein

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16
Q

DMTI

A

iron into duodenal enterocyte

17
Q

ferroportin

A

enterocyte to ferratin

18
Q

hepicidin

A

down regulates ferroportin

19
Q

anaemia of chronic disease

A

increased hepicidirin