Renal/Urology Flashcards

1
Q

triad of haemolytic uraemic syndrome

A

AKI
haemolytic anaemia
thrombocytopenia

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2
Q

CKD can lead to what complication that may cause fractures?

A

secondary hyperparathyroidism

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3
Q

define AKI in terms of urine output

A

<0.5ml/kg/hr

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4
Q

Define AKI in terms of creatinine

A

creatinint rise of >26mmol/l in 48 hours

OR

50%+ rise in serum creatinitne to occur within the past 7 days

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5
Q

which drugs should be stopped in AKI

A

NSAIDs
aminoglycosides
ACEis, ARBs
diuretics

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6
Q

treatment of hyperkalaemia

A

IV calcium gluconate

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7
Q

treatment of hyperphosphataemia in patients with CKD

A

sevelamer

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8
Q

how to screen for diabetic neurpathy?

A

albumin:creatinine ratio (early morning)

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9
Q

most common extra renal manifestation of ADPKD?

A

liver cysts

berry aneurysms

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10
Q

ABG in AKI

A

Metabolic acidosis with raised anion gap

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11
Q

Maintenane fluids in children?

A

100ml per first 10kgs
50ml per next 10kgs
20ml for every subsequent kg

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12
Q

most common cause of nephrotic syndrome in children?

A

minimal change disease

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13
Q

indications for dialysis

A

hyperkalaemia
acidosis
uraemia

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14
Q

what drugs to stop in AKI

A

diuretics
ACE inhibitors
metformin
NSAIDs

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15
Q

blood results in haemolytic uraemic syndrome?

A

normocytic anaemia
thrombocytopenia
AKI

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16
Q

potassium requirement for adults per day in fluids?

A

1mmol/kg/day

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17
Q

water requirements for an adult in 24 hours?

A

25-30ml/kg/day

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18
Q

risk of 0.9% normal saline in patients that require a lot of fluid?

A

hyperchloraemic mtabolic acidosis

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19
Q

when is hartmann’s contraindicated

A

in patients weith hyperkalaemia

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20
Q

treatment of goodpasture’s syndrome

A

plasma exchange
steroids
cyclophosphamide

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21
Q

what is seen on renal biopsy in good pastures?

A

IgG deposits on the basement membrane

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22
Q

antihypertensive that may cause hyperkalaema

23
Q

how to move potassium from the extracellular compartment into cells?

A

insulin/dextrose infusion

nebulised salbutamol

24
Q

what is rhabdomyolisis

A

destruction of skeletal muscle

25
Indication that kidney disease is chronic, not acute?
hypocalcaemia
26
what do the kidneys look like on ultrasound in chronic kidney failure?
bilateral small kidneys
27
why do patients with CKD get anaemic?
reduced erythropoetin
28
prevention of ascites
spironolactone (aldosterone antagonist)
29
adverse effects of spironolactone
hyperkalaemia | gynaecomastia
30
haematrie following an URTI?
IgA nephropathy
31
what is stage 1 AKI?
creatinine increase in 1.5-1.9x the baseline or 6 hours reduced urine output
32
what is stage 2 AKI?
creatinine increase 2-2.9x the baseline or 12 hours reduced urine output
33
what is stage 3 AKI?
creatinine increase 3x baseline
34
what characterises diabetes insipidus
high plasma osmolality, low urine osmolality
35
what does IV calcium gluconate do?
stabilising the cardiac membrane (when a patient is hyperkalaemic)
36
Treatment of nephrotic syndrome/minimal change disease in children
oral steroids + urgent outpatient referral to paeds
37
what infection are people who have had organ transplants most likely to get?
cytomegalovirus
38
treatment of cytomegalovirus
ganciclovir
39
what causes peritonitis secondary to peritoneal dialysis?
staph epidermidis
40
HSP classic symptoms
rash, joint pain, abdo pain, haematuria
41
treatment of rhabdomyolysis is?
rapid IV fluid hydration with normal saline
42
most common cause of nephrotic syndrome in adults?
focal segmental glomeruloscerosis
43
urine sodium is high in....
acute tubular necrosis
44
urine sodium is low in....
pre renal uraemia
45
rhabdomyolusis causes what to happen to the kidneys
tubular cell necrosis
46
what is the effect on the parathyroid in CKD?
secondary hyperparathyroidism
47
blood in urine weeks after infection?
post strep glomerulonephritis
48
blood in urine days after infection?
IgA nephropathy
49
why is there a risk of thrombosis in nephrotic syndrome?
loss of antithrombin III
50
what happens to thyroxine in nephoritc syndrome?
low total thyroxine
51
sterile pyuria and white cell casts indicate...?
acute interstitial nephritis
52
causes of renal artery stenosis
atherosclerosis | fibromuscular dysplasia
53
how is amyloidosis diagnosed
rectal biopsy