๐ฅ- Renal Test Flashcards
Normal BUN level
8-21 mg/dL
Normal serum creatinine level
0.5-1.2 mg/dL
Oliguria
Decreased amount of urine output, 100-400 mL in 24hrs
What are the 3 ways the kidneys maintain homeostasis
Urine formation and waste excretion
Regulatory function (fluid, acid-base balance, electrolytes)
Hormonal function
List 3 hormones produced by the kidney
Renin
Erythropoietin
Activated vitamin d
Glycosuria
Glucose in urine as a result of blood sugar greater than 220 mg/dL
Kidneys function to maintain balance of
Water
Electrolytes
Acid-base
Regulatory intake
2,500 mL/day
Metabolic water- 200mL
Food- 700mL
Drink- 1,600mL
Regulatory output
2,500 mL/day
Feces- 200mL Expired air- 300mL Cutaneous transpiration- 400mL Sweat- 100mL Urine- 1,500mL
Water balance by the kidneys prevents what
Enable the kidneys to control the volume and concentration of urine independently from fluid intake
Prevent dehydration when fluid intake is low
Prevent volume overload when fluid intake is excessive
Acid base balance - acidosis
Kidneys excrete H+ and reabsorb bicarb to INCREASE pH (make less acidic)
Acid base balance- alkalosis
Kidneys reabsorb H+ and excrete bicarb to DECREASE pH (make less alkolodic)
What causes renin to be produced
When receptors in the kidneys sense a decrease in blood flow, volume or pressure AND/OR when decreased levels of Na+ in the blood is detected
What is the flow of angiotensin II formation
Renin from kidneys + angiotensinogen from liver = angiotensin I
Angiotensin I + angiotensin-converting enzyme (ACE) from lungs = angiotensin II
Angiotensin II
Constricts blood vessels, causing increased BP
Stimulates adrenal gland to release aldosterone
Stimulates the hypothalamus to stimulate thirst
Aldosterone
Causes increased Na+ reabsorption and subsequent water reabsorption in the DCT
Activated vitamin d
- vitamin d is obtained from diet and UV radiation
- vitamin d is converted to calcidiol in the liver
- calcidol is converted to calcitriol in the kidneys
- ACTIVATED FORM OF VITAMIN D IS REQUIRED FOR CA+ TO BE ABSORBED IN THE GI TRACT*
Which electrolyte has an inverse relationship with Ca+
Phosphate
Low Ca+ in renal impairment usually has increased phosphate
How many times a day should an average adult void
5-6
And doesnโt regularly need to void overnight
Anuria
Total urine output of less than 100 mL in 24hrs
Normal BUN/creatinine ratio
10:1 - 20:1
Polyuria
Increased urine output ; greater than 2,000 mL in 24hrs
Normal range of specific gravity
1.005 - 1.030
Normal pH of urine
4.5-8
Bacteria in urine
Should be less than 1,000 colonies/mL
An increased osmolality can mean what
Indicates diabetes mellitus, dehydration, fever
A decreased osmolality can mean what
Indicates renal insufficiency, diabetes insipidus, diuretic use
Composite urine collection
Collecting all urine voided for a defined period of time ranging between 2 and 24hrs
*sample should be refrigerated or kept on ice for the duration of collection
Urine cytology
Used to identify any abnormal cells preset in the urine
Intravenous urography
Requires the administration of radiographical dye (contrast) via an IV line
Preprocedure instructions for IV urography
- bowel preparation and NPO approximately 8hrs before
- may feel brief flushing sensation and a salty taste in mouth during injection of contrast
- signed informed consent
- baseline serum creatinine (nephrotoxic)
- allergies
Postprocedure instructions for IV urography
- increase fluid intake
- Monitor for changes in urine output, irritation at IV site and delayed signs of reaction to contrast