renal system Flashcards

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1
Q

layers of the kidney

A

Cortex – outer zone, granular
Medulla – inner zone made of renal pyramids, divided into lobes
Renal pelvis – funnel-shaped, continuous with ureter

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2
Q

Cortical nephrons

A

which lie predominantly in the renal cortex and their Loop of Henle dips into the renal medulla.

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3
Q

Juxtamedullary nephrons

A

lie at the cortex-medulla junction and have long nephron loops that are located deep in the medulla.

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4
Q

vascular components

A

Abdominal aorta
Renal artery
Afferent arteriole
Glomerulus (capillaries)
Efferent arteriole
Peritubular capillaries
Renal vein
Inferior vena cava

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5
Q

tubular components

A

Renal corpuscle (Glomerulus and Bowman’s capsule)
Proximal convoluted tubule (PCT)
Loop of Henle (nephron loop)
Distal convoluted tubule (DCT)
Collecting duct

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6
Q

urine flow

A

urine drains out of pyrimids
minor claycles
major claycles
renal pelvis
ureter
urinary bladder
urethra

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7
Q

ureters

A

Muscular tubes that transport urine from renal pelvis to urinary bladder by peristalsis.

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8
Q

urethra

A

In the female, the urethra serves as a passage for urine.
In the male, there are three parts: prostatic, membranous and penile. It serves for the passage of semen and urine.
In both female and male it has a voluntary external sphincter (striatal muscles).

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9
Q

urinary bladder

A

Hollow, muscular organ that stores urine before voiding.
It is a powerful detrusor muscle (smooth muscle).
Has internal urethral sphincter (smooth muscle).

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10
Q

primary functions of the renal system

A

Excretion (metabolic waste and foreign substances such as drugs)
Acid-base balance (regulate concentration of ions e.g. Hydrogen ions)
Osmoregulation (regulate total volume of water and total concentration of solutes in that water).

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11
Q

secondary functions of the urinary system

A

Blood pressure maintenance (regulate water and solute concentration)
Anaemia correction (produce erythropoietin, regulating red blood cell production)
Calcium regulation
Protein catabolism – urea
Detoxification (removes toxins and waste).

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12
Q

glomerular filtration rate

A

(urine concentration) x (urine flow rate) / (serum creatine concetration)

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13
Q

glomerular hydrostatic pressure

A

pressure exerted on the walls of the capillaries by fluid

this forces fluid out of capilaries into the bowemens capsule

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14
Q

colloid osmotic pressure

A

is exerted by plasma proteins remained in the blood
pulling fluid back towards the capillaries

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15
Q

capsular hydrostatic pressure

A

pressure exerted by fluids from bowemans capsule into the blood vessels

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16
Q

autoregulation of blood pressure

A

decreased blood pressure
decrease in GFR
afferent vessels vasodilate
increase glomerular hydrostatic pressure
increase GFR

17
Q

hormones that have an affect on blood pressure here

A

angiostein- vasoconstriction// stimulates aldosterone and ADH

ADH- increase water reabsorption- increase blood volume and pressure

aldosterone- retains more Na+ ions so water is reabsorbed

ANP/ BNP= stop ADH AND ALDONSTERONE

18
Q

Urine formation steps

A

glomerular filtration

tubular reabsorption

tubular secretion

19
Q

glomerular filtraton

A

water and blood solutes move from blood capillaries/ glomerulus into bowemans capsule

pressure pushes these materials
ions/ water/ glucose

non selective

20
Q

tubular reabsorption

A

proximal convuluted tubular

selective process

filtrate of water/ glucose/ ions move back into blood

21
Q

tubular secretion

A

selective process
wastes Hplus drugs

22
Q

glycosuria

A

glucose in urine

if not fully reabsorbed

23
Q

water reabsorption

A

obligatory- solutes go then water goes too= osmosis
factulative- hormone reabsorption

24
Q

micturition reflex

A

Filling of the bladder is enabled by:

Contraction of internal urethral sphincter
Inhibition of detrusor (bladder) muscle activity.
Emptying of the bladder is enabled by:
contraction of the detrusor (bladder) muscle
relaxation of the internal and external sphincters

25
Q

ageing and renal system

A

Sphincter loses muscle tone which leads to incontinence
Urinary retention if prostate enlarged.
Decreased number of functional nephrons:

↓ GFR due to fewer glomeruli
Deterioration in filtration, reabsorption and endocrine functions
Nephrons become less sensitive to ADH.

26
Q
A