pharmocology

Question 1

pharmacology

Answer 1

study of drugs
actions and effects on the systems

Question 2

drug

Answer 2

substance or product that is used to modify physiological system that provide benefits to the user

Question 3

medicine

Answer 3

drug mixed in formulation that is able to be administered

Question 4

administer drugs

Answer 4

how the drug works
how the drugs affects the body
usual dosage, frequency,
effects and indications
adverse affects
drug intereactions

Question 5

useful drug characteristics

Answer 5

1. potent= amount of chemical required to produce an effect
2. selective- act on particular cellular process
3. easily adminstered
4. easy to absorb
5. easy to eliminate

Question 6

Pharmaceutics

Answer 6

The science of the preparation and dispensing of drugs

Question 7

chemical name

Answer 7

precise description of drugs chemical composition

Question 8

approved name

Answer 8

name suggested by regulatory body

Question 9

trade name

Answer 9

what its sold as

Question 10

pharmocokenetics

Answer 10

drug absorption, distribution, excretion

Question 11

drug absorption

Answer 11

passage of drug from site of administed into blood stream

must cross cell membrane ( passive diffusion filtration, active transport)

Question 12

what determines absorption

Answer 12

number of cell membranes

surface area

blood stream

-lipid soluble, degree of ionisation, ph, molecular structure

Question 13

how does drug travel in blood

Answer 13

in a drug protein complex

Question 14

how does distribution effected

Answer 14

hypoalbumin
affinity of the drug to bind to protein
drugs bind to other tissues
drug brairers

Question 15

drug metabloisim

Answer 15

start of drug clearence occurs in the liver

occurs in the liver

enzyme modification

lipid soluble to water soluble

kidney- get rid of drug

Question 16

the process of drug metabolisim

Answer 16

oxidation
reduction
hydrolysis
conjuction

try to get the lipid soluble to be water soluble

Question 17

hepatic first pass effect

Answer 17

variable proprotion of orally adminstered drug
that is metabolised by liver before it has an effect on the body

Question 18

renal drug excretion

Answer 18

glomerular filtration- only free unbound drugs- not bound to albumin

tubular secretion- drugs may be reabsorbed depending on their lipid solubility- if its lipid soluble will be reabsorbed

tubular

Question 19

drug clearence

Answer 19

hepatic + renal + other

Question 20

four regulatory drugs proteins

Answer 20

receptors
ion channels
carrier molecules
enzymes

Question 21

receptors

Answer 21

lock and key

agonist- increase response
antagonist- stop

Question 22

ion channels

Answer 22

block channels- stop action potential maybe

acts as a chemical receptor

Question 23

carrier molecules

Answer 23

prevent uptake of carrier molecules - can’t uptake of neurotransmitter

Question 24

enzymes

Answer 24

non- competitive inhibitor- denatures the binding site can’t procced at all oftern perment

competitive inhibitor - active site