Renal Flashcards
% of body weight that is TBW, ICF, and ECF
60% TBW, 40% ICF, 20% ECF
Renal clearance equation:
CL = (UV) / P (U=urine conc, P=plasma conc, V=urine flow rate)
GFR equation:
GFR = clearance of inulin (UV/P) GFR = Kf [starling pressure]
How do you calculate Effective Renal Plasma Flow?
Using clearance of PAH (UV/P)
How is renal blood flow related to hematocrit?
RBF = RPF/(1-Hct)
How do you calculate Filtration Fraction?
FF = GFR / RPF; normal FF=20%
How do you calculate Filtered Load?
Filtered load (mg/min) = GFR (mL/min) x plasma concentration (mg/mL) FL = GFR x P
How do you calculate Excretion rate?
Excretion rate = V x U
What is Hartnup Disease?
Autosomal recessive deficiency of neutral amino acid transporters in proximal renal tubule and enterocytes. Pellagra-like symptoms.
What is the Henderson-Hasselbach equation?
pH = 6.1 + log [HCO3-] / (0.03 x PCO2) pCO2 = 1.5 [HCO3-] + 8 (+/- 2)
What is the equation for anion gap?
Anion gap = Na - (Cl + HCO3)
RBC casts found in:
Glomerulonephritis, ischemia, or malignant hypertension
WBC casts found in:
Tubulointerstitial inflammation, acute pyelonephritis, transplant rejection
Fatty casts found in:
= “oval fat bodies”. Nephrotic syndrome
Granular casts found in:
=”muddy brown”. Acute tubular necrosis
