Autoantibodies and associated Dz Flashcards

1
Q

Anti-ACh receptor

A

Myasthenia Gravis

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2
Q

Anti-basement membrane

A

Goodpasture syndrome

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3
Q

Anti-cardiolipin

A

= lupus anticoagulant –> antiphospholipid syndrome, SLE,

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4
Q

Anti-centromere

A

Limited Scleroderma (CREST)

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5
Q

Anti-desmoglein

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA, anti-Smith

A

SLE

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7
Q

Anti-glutamate decarboxylase

A

Type 1 diabetes mellitus

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Anti-histone

A

Drug-induced Lupus

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10
Q

Anti-Jo-1, anti-SRP, anti-Mi-2

A

Polymyositis, dermatomyositis

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11
Q

Anti-microsomal

A

Hashimoto thyroiditis

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12
Q

Anti-thyroglobulin

A

Hashimoto thyroiditis

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13
Q

Anti-mitochondrial

A

Primary biliary cirrhosis

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14
Q

Anti-nuclear antibodies

A

SLE, nonspecific

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15
Q

Anti-Scl-70

A

(anti-DNA topoisomerase I) Diffuse scleroderma

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16
Q

Anti-smooth muscle

A

Autoimmune hepatitis

17
Q

Anti-SSA, Anti-SSB

A

Sjogren syndrome

18
Q

Anti-Ro, Anti-La

A

Sjogren syndrome

19
Q

Anti-TSH receptor

A

Graves disease

20
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

21
Q

c-ANCA (PR3-ANCA)

A

Granulomatosis with polyangiitis (Wegener’s)

22
Q

IgA Antiendomysial, IgA anti-tissue transglutaminase

A

Celiac disease

23
Q

p-ANCA (MPO-ANCA)

A

Microscopic polyangiitis, Churgg-Strauss syndrome

24
Q

Rheumatoid factor, anti-CCP

A

Rheumatoid Arthritis (Anti-CCP more specific)