Renal Flashcards
1
Q
Ischaemia leads to inflammatory response in the kidney by which 3 mechanisms?
A
ATP depletion (necrosis)
Increased hypoxia inducible factor (HIF)
Reactive oxygen species generation (ROS)
2
Q
Vasopressin/adh acts on which receptor in the kidney
A
V2 receptor
3
Q
What is the equation for renal blood Flow?
A
RBF= (renal artery pressure- renal vein pressure)/ total renal vascular resistance
4
Q
What G protein is V2 receptors linked with and what secondary messenger?
A
Gs and cyclic AMP —-> protein kinase A
5
Q
What is the overall survival to discharge for dogs with AKI?
A
50-70%
Vaden JVIM 56%
Legatti Plos One 55%
Rimer JVIM 67%
6
Q
What is the definition of IRIS AKI grade I?
A
Increase in 0.3mg/dL or 26.4umol/L
