Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

ph 107 - pharmaceutical dosage forms, drug delivery systems, and medical devices (lec.) > Radiopharmaceuticals > Flashcards

Radiopharmaceuticals Flashcards

You may prefer our related Brainscape-certified flashcards:
USMLE® Step 1 flashcards
1
Q

Is a radioactive pharmaceutical agent that is used for diagnostic or therapeutic procedure

A

Radiopharmaceutical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Substances that have the same number of protons but have varying numbers of neutrons

A

Radionuclide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Decay equation

A

Ae = Ao^-λt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Represents specific gravity at time t (Decay equation)

A

Ae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Represents initial activity (Decay equation)

A

Ao

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Represents the decay constant calculated as In 2/ half-life

A

λ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Represents time (Decay equation)

A

t

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The fundamental unit of radioactivity; defined as 3.7x10^10 nuclear transformation per second or disintegrations per second (dps)

A

Curie (Ci)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Radiopharmaceuticals that deliver the minimum possible radiation dose to the patient while still obtaining the required diagnostic information

A

Diagnostic radiopharmaceuticals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Radiopharmaceuticals that deliver the maximum radiation dose to the diseased organ or tumor while minimizing the radiation dose to nontarget tissues

A

Therapy radiopharmaceuticals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

A metastable nuclear isomer of technetium 99, the most commonly used medical radioisotope

A

Technetium-99m (99m Tc)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Half-life of Technetium-99m (99m Tc)

A

1 day/24 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

An isotope of yttrium; used in radiation therapy to treat cancer

A

Yttrium-90 (90 Y)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Half-life of Yttrium-90 (90 Y)

A

64.1 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

A diagnostic radiopharmaceutical indicated for myocardial perfusion imaging for the diagnosis of coronary artery disease

A

Thallous-201 chloride (201 Tl)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Meaning of SPECT

A

Single-photon emission computed tomography

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Used as a radioactive tracer to obtain images of a specific type of tissue, or disease state of tissue

A

Gallium-67 citrate (67 Ga)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

An isotope of indium that is useful for isotopic labeling of blood cell components

A

Indium-111 chloride (111 In)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Half life of Indium-111 chloride (111 In)

A

2.8 days

20
Q

Used in nuclear imaging; used for the diagnostic study of thyroid diseases

A

Sodium iodide-123 (123 I)

21
Q

Half life of Sodium iodide-123 (123 I)

A

13.13 hours

22
Q

An isotope used to treat hyperthyroidism and certain thyroid cancer

A

Sodium iodide-131 (131 I)

23
Q

Emits beta particles and gamma rays; it localizes selectively in the bone and is used in palliation of bone cancer

A

Samarium-153 (153 Sm)

24
Q

This isotope is useful in calibration of gamma ray spectrometers

A

Holmium-166 (166 Ho)

25
Q

This synthetic isotope is bound to ocreotate and is used in targeted radionuclide therapy for neuroendocrine tumors and bone pain palliation

A

Lutetium-177 (177 Lu)

26
Q

2 isotopes that are used for bone palliation, endo-radiotherapy, tumor therapy

A

Rhenium-186 & Rhenium-188 (186/188 Re)

27
Q

Therapy where the absorbed dose to be delivered should be determined from uptake measurements, effective half-life of the radiopharmaceutical and the size of the thyroid

A

I-131 therapy

28
Q

Is a local intraarticular injection of radionuclides in colloidal form of radiotherapy

A

Radiosynovectomy

29
Q

A kind of care that makes a person feel better even if it does not cure the disease

A

Palliation

30
Q

Involves the IV injection of a radiopharmaceutical

A

Pain palliation

31
Q

Imaging that detects function properties of the human tissue

A

Nuclear imaging

32
Q

Type of imaging where the distribution of the pharmaceutical is fixed over the imaging period

A

Static imaging

33
Q

Type of imaging where the camera scans over the whole body to cover more widespread distributions or unknown locations

A

Whole body imaging

34
Q

Type of imaging where consecutive images are acquired over a period of time showing the changing distribution of the radiopharmaceutical in the organ of interest

A

Dynamic imaging

35
Q

Scan that reflects bone metabolism and blood flow, and allows functional analysis of bone turnover

A

Bone uptake

36
Q

Scan where a proportionately spread embolization of the pulmonary capillary bed yields an image reflection the lung blood perfusion

A

Lung scan

37
Q

Scan that offers structural and functional information by displaying the thyroid image and calculating uptake, organ volume, etc.

A

Thyroid scintigraphy/scan

38
Q

Reflects renal blood perfusion, uptake, and excretion

A

Dynamic renal scintigraphy

39
Q

Meaning of PET

A

Positron emission tomography

40
Q

4 isotopes used in PET

A

Carbon-11, Nitrogen-13, Fluorine-18, Oxygen-15

41
Q

Is a radioactive isotope of carbon that decays to boron-1; it is used in radioactive labeling of molecules in PET

A

Carbon-11

42
Q

Is a radioisotope of nitrogen used in PET, primarily to tag ammonia molecules for PET myocardial perfusion

A

Nitrogen-13

43
Q

Is a radioisotope synthesized into fluorodeoxyglucose (FDG) for use in PET scans and used for labelling antibodies that allows for PET imaging of cancer

A

Fluorine-18

44
Q

Is a radioisotope of oxygen used in PET-imaging; it is synthesized through deuteron bombardment of nitrogen-14 using a cyclotron

A

Oxygen-15

45
Q

Machine that works by using a scanning device to detect positrons (subatomic particles) emitted by a radionuclide in the organ or tissue being examined

A

PET scanner

46
Q

An apparatus in which charged atomic and subatomic particles are accelerated by an alternating electric field while following an outward spiral or circular path in a magnetic field

A

Cyclotron

ph 107 - pharmaceutical dosage forms, drug delivery systems, and medical devices (lec.) (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions