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PH 107 - Pharmaceutical Dosage Forms, Drug Delivery Systems, and Medical Devices (Lec.) > MISC 03 - Pre-Finals Quizzes > Flashcards

MISC 03 - Pre-Finals Quizzes Flashcards

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USMLE® Step 1 flashcards
1
Q

Which among the following statements is NOT TRUE for elixirs?

a. Elixirs are more viscous than syrups
b. Elixirs are clear and pleasantly flavored intended for oral use
c. Elixirs contain 5-40% alcohol
d. Elixirs are less sweet than syrups

A

a. Elixirs are more viscous than syrups

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2
Q

Freely soluble

a. 10-30
b. 1-10
c. 100-1000
d. 30-100

A

b. 1-10

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3
Q

Soluble

a. 10-30
b. 1-10
c. 100-1000
d. 30-100

A

a. 10-30

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4
Q

Sparingly soluble

a. 10-30
b. 1-10
c. 100-1000
d. 30-100

A

d. 30-100

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5
Q

Slightly soluble

a. 10-30
b. 1-10
c. 100-1000
d. 30-100

A

c. 100-1000

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6
Q

Used for the treatment of nasopharyngeal condition by forcing air from the lungs through a gargle that is held in the throat and subsequently expectorated

a. Juices
b. Gargle
c. Douche
d. Mouthwash

A

b. Gargle

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7
Q

Mucilages are prone to decomposition and should never be made in large quantities that can be used immediately unless a preservative is added

a. True
b. False

A

a. True

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8
Q

Juices are expressed juices prepared from fresh ripe fruits, used in syrups which are employed as vehicles. Freshly expressed juices are preserved with benzoic acid allowed to stand at room temperature for several days until all pectin naturally present are destroyed by enzymatic action

a. True
b. False

A

a. True

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9
Q

SPIRITS are also known as ESSENCES and may be used pharmaceutically as flavoring agents and medicinally for the therapeutic value of the solute. Spirits contain NLT 80% of alcohol.

a. True
b. False

A

b. False (NLT 60% alcohol)

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10
Q

OLEOVITAMINS are fish liver oils diluted with edible vegetable oil or solution of the indicated vitamins or vitamin concentrate (usually Vitamin B & D) in fish liver oil

a. True
b. False

A

b. False (Vitamin A & D)

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11
Q

Oral rehydration solutions (ORS) are used for the treatment of patients with mild depletion (5-10%) of body weight, is composed of the following, EXCEPT:

a. 25g Dextrose
b. 45 mEq K
c. 20 mEq Cl
d. 30 mEq citrate

A

b. 45 mEq K

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12
Q

It is also known as CLYSTER, and commonly used for bowel cleansing and relieve constipation

a. Mucilage
b. Irrigations
c. Douche
d. Enemas

A

d. Enemas

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13
Q

Solutions or mixture of various substances in oil, alcoholic solution of soap, or emulsions, intended for external application.

a. Mucilage
b. Oleovitamins
c. Liniments
d. Collodions

A

c. Liniments

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14
Q

Acacia mucilage

a. Simple solution with maceration
b. Chemical reaction
c. Percolation
d. Direct solution
e. Alternate solution
f. Dispersion of gum in water

A

f. Dispersion of gum in water

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15
Q

Simple syrup

a. Simple solution with maceration
b. Chemical reaction
c. Percolation
d. Direct solution
e. Alternate solution
f. Dispersion of gum in water

A

c. Percolation

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16
Q

Peppermint spirit

a. Simple solution with maceration
b. Chemical reaction
c. Percolation
d. Direct solution
e. Alternate solution
f. Dispersion of gum in water

A

a. Simple solution with maceration

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17
Q

Belladonna tincture

a. Simple solution with maceration
b. Chemical reaction
c. Percolation
d. Direct solution
e. Alternate solution
f. Dispersion of gum in water

A

c. Percolation

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18
Q

Cinnamon water

a. Simple solution with maceration
b. Chemical reaction
c. Percolation
d. Direct solution
e. Alternate solution
f. Dispersion of gum in water

A

d. Direct solution

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19
Q

Concentrated peppermint water

a. Simple solution with maceration
b. Chemical reaction
c. Percolation
d. Direct solution
e. Alternate solution
f. Dispersion of gum in water

A

e. Alternate solution

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20
Q

Ethyl nitrate spirit

a. Simple solution with maceration
b. Chemical reaction
c. Percolation
d. Direct solution
e. Alternate solution
f. Dispersion of gum in water

A

b. Chemical reaction

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21
Q

Mouthwash, mouth rinse, oral rinse or mouth bath, is a liquid which is held in the mouth passively or swilled around the mouth by contraction of the perioral muscles and/or movement of the head

a. True
b. False

A

a. True

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22
Q

Tinctures are alcoholic or hydroalcoholic solutions prepared from vegetable or chemical substances

a. True
b. False

A

a. True

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23
Q

Preparation of pharmaceutical water wherein there is a passage of water through a column of cation & anion exchangers consisting of resins producing demineralized or deionized water

a. Reverse osmosis
b. Distillation
c. Ion-exchange

A

c. Ion-exchange

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24
Q

Collodions is/are syrupy solution of pyroxylin in a mixture of ether and alcohol (2:1); and often used as protectant

a. True
b. False

A

b. False (3:1)

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25
Q

Factors affecting solubility, EXCEPT:

a. Temperature
b. Pressure
c. Physical agitation
d. pH of the solution
e. None of the above

A

e. None of the above

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26
Q

Rubbing alcohol (70% ethanol alcohol) is composed of the following, EXCEPT:

a. 8 parts of acetone
b. 1.5 parts of methyl iso-propyl ketone
c. 100 parts of ethyl alcohol
d. None of the above

A

b. 1.5 parts of methyl iso-propyl ketone

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27
Q

Soaking using percolator

a. Decoction
b. Infusion
c. Percolation
d. Digestion

A

c. Percolation

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28
Q

Addition of hot/cold water

a. Decoction
b. Infusion
c. Percolation
d. Digestion

A

b. Infusion

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29
Q

Boiling for 15 minutes

a. Decoction
b. Infusion
c. Percolation
d. Digestion

A

a. Decoction

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30
Q

Applying of gentle heat

a. Decoction
b. Infusion
c. Percolation
d. Digestion

A

d. Digestion

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31
Q

Surfactants with HLB value (3-6) are greatly hydrophilic and produce O/W emulsions

a. True
b. False

A

b. False (W/O emulsions)

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32
Q

This usually operate between 35-55 pig at 70°F and may contain only 6-10% propellant

a. Foam aerosols
b. Surface aerosols
c. Space aerosols
d. None of the options

A

a. Foam aerosols

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33
Q

Emulsifying agent with greater hydrophilic character promotes an O/W emulsion → W/O emulsion through use of more hydrophobic emulsifiers

a. Plastic film theory
b. Surface tension theory
c. Viscosity theory
d. Oriented wedge theory

A

d. Oriented wedge theory

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34
Q

Qualities required for emulsifiers, EXCEPT:

a. Compatible with other ingredients
b. Non-toxic
c. Interfere with the therapeutic efficacy
d. Promote emulsification
e. Maintain stability for intended shelf life

A

c. Interfere with the therapeutic efficacy

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35
Q

Polyethylene gel

a. Hydrogels
b. Organogels

A

b. Organogels

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36
Q

Pectin paste

a. Hydrogels
b. Organogels

A

a. Hydrogels

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37
Q

Cocoa butter

a. Hydrogels
b. Organogels

A

b. Organogels

38
Q

Bentonite gel

a. Hydrogels
b. Organogels

A

a. Hydrogels

39
Q

Veegum

a. Hydrogels
b. Organogels

A

a. Hydrogels

40
Q

This means taking up a certain amount of liquid WITHOUT INCREASE IN VOLUME

a. Syneresis
b. Swelling
c. Imbibition
d. Thixotropy

A

c. Imbibition

41
Q

Joining together of globules to form large lumps/ floccules rising and settling more rapidly than the individual particles

a. Breaking
b. Coalescence
c. Flocculation
d. Creaming

A

c. Flocculation

42
Q

White lotion

a. Trituration
b. Chemical reaction
c. By hydration

A

b. Chemical reaction

43
Q

Milk of bismuth

a. Trituration
b. Chemical reaction
c. By hydration

A

b. Chemical reaction

44
Q

Milk of magnesia

a. Trituration
b. Chemical reaction
c. By hydration

A

c. By hydration

45
Q

Calamine lotion

a. Trituration
b. Chemical reaction
c. By hydration

A

a. Trituration

46
Q

Aerosols are pressured dosage forms containing one or more active ingredients upon actuation emit a fine dispersion of liquid and/or solid materials in gaseous medium

a. True
b. False

A

a. True

47
Q

Suspension is defined as coarse dispersion of finely divided drug particles called suspensoid distributed uniformly throughout a vehicle in which the drug exhibits minimum degree of solubility

a. True
b. False

A

a. True

48
Q

Make a mucilage (acacia + water) then add oil slowly

a. Wet gum method
b. Dry gum method
c. Forbes bottle method
d. In situ soap method

A

a. Wet gum method

49
Q

Continental method

a. Wet gum method
b. Dry gum method
c. Forbes bottle method
d. In situ soap method

A

b. Dry gum method

50
Q

Soap is formed (oil + aq soln in alkali)

a. Wet gum method
b. Dry gum method
c. Forbes bottle method
d. In situ soap method

A

d. In situ soap method

51
Q

Oil added to acacia in a bottle (3:2:1)

a. Wet gum method
b. Dry gum method
c. Forbes bottle method
d. In situ soap method

A

c. Forbes bottle method

52
Q

Cosmetic hair lacquers

a. Space sprays
b. Surface sprays

A

b. Surface sprays

53
Q

Room disinfectant

a. Space sprays
b. Surface sprays

A

a. Space sprays

54
Q

Space insecticides

a. Space sprays
b. Surface sprays

A

a. Space sprays

55
Q

Shaving lathers

a. Space sprays
b. Surface sprays

A

b. Surface sprays

56
Q

Paint sprays

a. Space sprays
b. Surface sprays

A

b. Surface sprays

57
Q

This means taking up of liquid by a gel WITH AN INCREASE IN VOLUME

a. Swelling
b. Imbibition
c. Syneresis
d. Thixotropy

A

a. Swelling

58
Q

This usually operate at pressures between 30-40 psig at 70°F and may contain as much as 85% propellant

a. Foam aerosols
b. Surface aerosols
c. Space aerosols
d. None of the options

A

c. Space aerosols

59
Q

A method of identifying emulsions which uses ultraviolet light

a. Fluorescence test
b. Dye solubility test
c. Conductivity test
d. Dilution method

A

a. Fluorescence test

60
Q

Surfactants with HLB values (8-18) produce O/W emulsions

a. True
b. False

A

a. True

61
Q

Sterilization by ionization radiation is a sterilization technique by gamma rays and by cathode rays, but application of such techniques is limited because of the highly specialized equipment required and the effects of radiation on products and their containers

a. True
b. False

A

a. True

62
Q

In 1652, intravenous medication was first given to humans by Johann Daniel Major of Kiel

a. True
b. False

A

b. False (1662)

63
Q

Animal model used for pyrogen test

a. Rabbit
b. Cat
c. Fish
d. Dog

A

a. Rabbit

64
Q

The goal of insulin therapy is to achieve tight blood glucose control by mimicking insulin secretion by the normal pancreas.

a. True
b. False

A

a. True

65
Q

It is not useful for oils, fats, oleaginous preparations and other preparations not penetrated by the moisture or for exposed powders that may be damaged by the condensed moisture

a. Gas sterilization
b. Steam sterilization
c. Dry heat sterilization
d. Sterilization by filtration

A

b. Steam sterilization

66
Q

Insulin aspart is a long-acting basal insulin preparation intended for once daily subcutaneous administration at bedtime in the treatment of type I Diabetes melitus in adults and children

a. True
b. False

A

b. False (Insulin glargine)

67
Q

Which is NOT true for steam sterilization?

a. 15 lb pressure (121.5°C or 250°F) for 20 mins
b. 10 lb pressure (115.5°C or 240°F) for 30 mins
c. 10 lb pressure (126.5°C or 260°F) for 35 mins
d. 20 lb pressure (126.5°C or 260°F) for 15 mins

A

c. 10 lb pressure (126.5°C or 260°F) for 35 mins

68
Q

Dry heat sterilization is usually conducted at 150° to 170°C for not less than 3 hours

a. True
b. False

A

b. False (2 hours)

69
Q

Microbial destruction is caused by denaturation & coagulation of bacterial proteins by moist heat and conducted in an autoclave and employs steam under pressure

a. Dry heat sterilization
b. Steam sterilization
c. Sterilization by filtration
d. Gas sterilization

A

b. Steam sterilization

70
Q

Parenteral routes are useful when, EXCEPT:

a. Rapid drug action is desired
b. Patient is uncooperative
c. Drug itself is ineffective by other routes
d. Patient is conscious
e. Patient is unable to accept or tolerate oral medication

A

d. Patient is conscious

71
Q

Time required to kill a particular organism under specified conditions

a. Thermal death time
b. Thermal mortality ratio
c. Thermal log death
d. None of the options

A

a. Thermal death time

72
Q

Bolus insulins are intermediate acting or long-acting insulins that mimic basal secretions of insulin

a. True
b. False

A

b. False (Basal insulin)

73
Q

Steam sterilization

a. Bacillus stearothermophilus
b. Bacillus subtilis
c. Bacillus pumilus

A

a. Bacillus stearothermophilus

74
Q

Ethylene oxide sterilization

a. Bacillus stearothermophilus
b. Bacillus subtilis
c. Bacillus pumilus

A

a. Bacillus stearothermophilus

75
Q

Dry heat sterilization

a. Bacillus stearothermophilus
b. Bacillus subtilis
c. Bacillus pumilus

A

b. Bacillus subtilis

76
Q

Vehicle for other drugs/alone as an electrolyte replenisher and plasma volume expander

a. Sodium chloride injection, USP
b. Lactated ringer’s injection
c. Water for injection, USP
d. Ringer’s injection, USP

A

d. Ringer’s injection, USP

77
Q

Sterile water for injection containing one or more suitable antimicrobial agents/ bacteriostatic agents and not intended for neonates

a. Bacteriostatic sodium chloride injection
b. Sterile water for injection, USP
c. Bacteriostatic water for injection, USP
d. Sodium chloride injection, USP

A

c. Bacteriostatic water for injection, USP

78
Q

Spinal fluid

a. Intra-articular
b. Intrathecal
c. Intracardiac
d. Intrasynovial
e. Intracutaneous

A

b. Intrathecal

79
Q

Joints

a. Intra-articular
b. Intrathecal
c. Intracardiac
d. Intrasynovial
e. Intracutaneous

A

a. Intra-articular

80
Q

Heart

a. Intra-articular
b. Intrathecal
c. Intracardiac
d. Intrasynovial
e. Intracutaneous

A

c. Intracardiac

81
Q

Skin

a. Intra-articular
b. Intrathecal
c. Intracardiac
d. Intrasynovial
e. Intracutaneous

A

e. Intracutaneous

82
Q

Joint fluid area

a. Intra-articular
b. Intrathecal
c. Intracardiac
d. Intrasynovial
e. Intracutaneous

A

d. Intrasynovial

83
Q

Basal insulin are rapid-acting or short-acting insulins that mimic the extra insulin the pancreas secrete in response to the post prandial rise in blood glucose levels

a. True
b. False

A

b. False (Bolus insulin)

84
Q

Requires specialized equipment resembling an autoclave and many combination steam autoclaves and ethylene oxide sterilizers and mainly used for sterilizing heat resistant & moisture resistant products

a. Sterilization by filtration
b. Dry heat sterilization
c. Gas sterilization
d. Steam sterilization

A

c. Gas sterilization

85
Q

Isophane Insulin suspension is a recombinant ultra-short acting insulin using Saccharomyces cerevisiae (baker’s yeast) as the production organism

a. True
b. False

A

b. False (Insulin aspart)

86
Q

Sterilization means destruction of all living organism and their spores or their complete removal from the preparation

a. True
b. False

A

a. True

87
Q

Lactated ringer’s injection contains, EXCEPT:

a. NaCl
b. KCl
c. MgCl2
d. Na lactate

A

c. MgCl2

88
Q

Biological indicator used for ionizing radiation sterilization:

a. Bacillus stearothermophilus
b. Bacillus pumilus
c. Bacillus subtilis
d. All of the choices

A

d. All of the choices

89
Q

Parenteral products are always sterilized, meet sterility standards, and must be pyrogen-free

a. True
b. False

A

a. True

90
Q

Oleaginous suspension can only be administered through this route and it is performed deep into the skeletal muscle

a. Intramuscular route
b. Subcutaneous route
c. Intradermal route
d. Intravenous route

A

a. Intramuscular route

PH 107 - Pharmaceutical Dosage Forms, Drug Delivery Systems, and Medical Devices (Lec.) (15 decks)

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