RAAS

Question 1

Actions of Angiotensin II

Answer 1

retains sodium, vasoconstriction, releases aldosteroe
-causes high BP and thick vessel walls

Question 2

ACE inhibitors
-what do they do?
-Most common side effect
-used for?
-route

Answer 2

inhibits ACE –> lowers BP
Also increases bradykinin –> cough
used for HF, MI, etc…
oral

Question 3

Adverse effects of ACE inhibitors

Answer 3

1st dose htn
teratogenic
COUGH
angioedema –> fucks up airway

Question 4

Angiotensin II receptor blockers
-compare to ACE inhib
-2 common types

Answer 4

-Don’t work as well as ACEi, but tolerated better and work the same –> don’t use at same time
-no bradykinin
-Losartan and Spironolactone (also blocks aldoseterone)

Question 5

Losartan side effects

Answer 5

low bp
other (fatigue headache dizziness)
swelling
allergic rxn
raised K
teratogenic
AKI (due to low perfusion) –>ELEVATED CREATINE
Nasal congestion