Other GI drugs

Question 1

Zofran
-class
-indication
-side effects

Answer 1

Antiemetic
indicated for chemo and withdrawal
adverse effects are headache, diarrhea, dizziness, LONG QT, and torsades de pointes

Question 2

Types of antiemetics

Answer 2

Benzos
Dopamine antagonists
Butyrophenones –> Haloperidol –> LONG QT
Metoclopramide (reglan) –> blocks dopamine in CTZ
Cannabinoids –> dronabinol

Question 3

what to give for motion sickness

Answer 3

Scopolamine
-makes old ppl crazy

Question 4

what to give for hyperemesis gravidarum

Answer 4

doxylamine and B6

Question 5

how well do antiemetics work in cancer patients

Answer 5

pretty well to prevent emesis, but not great at aborting it

Question 6

Antidiarrheas

Answer 6

opioids bc they cause constipation
Diphenoxylate and loperamide

Question 7

Drugs for IBS

Answer 7

Antispasmatics
bulk forming agents
antidiarrheals
tricyclic antidepressants

Question 8

how long do you have to have symptoms before it’s IBS

Answer 8

12 weeks

Question 9

IBD

Answer 9

crohns and UC
not curable

Question 10

Prokinetic agents
-what’s it do?
-what’s it used for?
-give an example

Answer 10

increase tone and motility of GI tract
used in GERD, CINV, and diabetic gastroparesis
Reglan