RA And OA Conditions Flashcards
Gouty arthritis is common among
Asians
SLE is common among
Africans/blacks
Most common site for inflammation in RA
Synovium
Pannus formation results to
Erosion
RA has reversible or irreversible deformities
Irreversible
The gene that may increase the risk of having RA
Only a predisposing factor
HLA DR4
Series of antibodies that recognizes IgG as an antigen
Rheumatoid factor(RF)
How many percent of pxs with RF has RA
70%
Positive for RF is called
Seropositive
Negative for RH factor is called
sero negative
Found in pxs whos sero positive
seen over the joints, extensor surfaces of FA and weight bearing areas
Rheumatoid nodules
Sero means
Blood
Oligo means
Few
Metabolism of dead cells
Citrollination
targets protein antibodies and doesnt want the process of eliminating or metabolising dead cells
Anticitrullinated protein antibody(ACPA)
Sx are aggraviated all throughout the day specially during WB
Osteoarthritis
Morning stiffness for at least 1 hour(should be >30 mins)
RA
No of joints affected to consider RA has poor prognosis
> 10 jts
No of joint on B hands(MCP,wrist,PIP)
20 joints
Erosion in X-Ray(ABCDES)
Abnormal alignment Bone involvement Cartilage involvement Deformity Erosion Soft tissue swelling
Found inside rheumatoid nodules
Necrotic tissues/deadcells
Out of the 7 criterias how many should be present and for how long?
4 criterias(1st 4) for 6 consecutive weeks
Perfect score for the grading of 2010 ACR-EULAR(european league against rheumatism)
Ideal score (most likely RA)
10
>6
Formula for ESR
Age+10 (divide by) 2