Quiz 3

Question 1

Onsior (robenacoxib) and meloxicam were presented in lecture as example of this drug class. They are pain relievers, non-controlled substances and decrease inflammation that may cause pain.

Answer 1

NSAIDs (Nonsteroidal Anti-inflammatory Drugs)

Question 2

This class of analgesic drugs have members that have multiple different types binding activity (agonists, partial agonists, agonist / antagonist). What is the class of analgesics?

Answer 2

Opioids

Question 3

Which of the following is/are an effect of NSAIDs?

Answer 3

• Inhibiting the activity of COX-1 and/or COX-2 enzymes
• Effective when incorporated into the surgical premedication protocol
• Can impair platelet function.

Question 4

Which of the following is/are an effect of Local Anesthetic Agents.

Answer 4

Inhibit transduction and transmission of nerve impulses

Question 5

Which of the following is / are signs of administering an anticholinergic / parasympatholytic?

Answer 5

• Bronchodilation
• Dilation of the pupils
• Increased cardiac output

Question 6

Which of the following is / are reasons some veterinarians do not use atropine in cats?

Answer 6

Cats can produce thick mucous causing E.T. tube obstruction as a result of atropine administration.

Question 7

Physostigmine is a reversal agent for…

Answer 7

Glycopyrrolate

Question 8

Alpha-2 agonists…

Answer 8

cause bradycardia, vasoconstriction and respiratory depression

Question 9

Which of the following opioid receptors when stimulated does NOT produce analgesia?

Answer 9

Sigma

Question 10

What are adverse effects of opioid use?

Answer 10

• Respiratory Depression
• Constipation
• Increased sensitivity to noise

Question 11

Which of the following is an example of neuroleptanalgesia

Answer 11

hydromorphone and midazolam

Question 12

Barbiturates are not commonly used in veterinary anesthesia. Which of the following barbiturates is primarily used as a Euthanasia Agent?

Answer 12

Pentobarbital

Question 13

Ketamine and Tiletamine are dissociative anesthetics. They cyclohexamines and are painful when administered IM. In addition…

Answer 13

-Ketamine can be used as a CRI and offers analgesia by inhibiting NMDA receptors in the CNS.
Tiletamine, in veterinary medicine, is combined with Zolazepam and sold as Telazol.
-They can have effects such as tachycardia , apneustic breathing, increased intraocular are CSF pressure.

Question 14

Ketamine is frequently given in conjunction with other agents to facilitate muscle relaxation.

Answer 14

ketamine and midazolam

Question 15

Propofol is an injectable hypnotic agent that in some areas of the country is a controlled substance. It is a white milky emulsion and can be used as an induction or maintenance when administered IV. In addition…

Answer 15

propofol has a rapid induction and should be titrated to effect.

Question 16

Which anesthetic agent is a neuroactive steroid that enhances GABAA receptors by allowing an influx of chloride ions into cells?

Answer 16

Alfaxalone

Question 17

Alfaxalone, when compared to Propofol….

Answer 17

• has less cardiovascular suppression
• has a lower risk of apnea
• is a federally controlled substance in the U.S.

Question 18

This anesthetic agent is a sedative hypnotic imidazole. It is administered IV and has minimal cardiovascular effects.

Answer 18

Etomidate

Question 19

Which of the following is/are adverse effects of Etomidate?

Answer 19

Painful IV injection
Vomiting
Formation of sterile abscesses with perivascular injection

Question 20

Which medication, frequently administered with other agents, is administered IV primarily as a muscle relaxant offering poor sedation and poor analgesia?

Answer 20

Guaifenesin

Question 21

Which of the following is NOT a Halogenated Organic Compound inhalation agent?

Answer 21

Nitrous Oxide

Question 22

Inhalation anesthetic agents enter the blood stream because of….

Answer 22

the concentration gradient and lipid solubility at the level of the alveoli

Question 23

What is the target organ for the anesthetic effect of inhalation agents?

Answer 23

Brain

Question 24

What is the main method of elimination of commonly used Anesthetic Inhalation Halogenated Organic Compounds?

Answer 24

Lungs

Question 25

An inhalation agent with a low Solubility / Partition Coefficient…

Answer 25

has a quick induction and recovery time.

Question 26

Which of the following is/are TRUE when comparing Sevoflurane and Isoflurane?

Answer 26

• Sevoflurane is less potent than Isoflurane.
• Sevoflurane has a quicker onset of action than Isoflurane
• Sevoflurane is a better choice for mask induction than Isoflurane.

Question 27

Based on MAC value, what is the target setting of a precision vaporizer using an inhalation agent to maintain a surgical plane of anesthesia?

Answer 27

1.5 x the MAC value

Question 28

What are some of the adverse effect(s) of most inhalation anesthetic agents?

Answer 28

• Respiratory Depression
• Decreased Glomerular Filtration Rate with the need to use caution with NSAIDs
• Depressed myocardial function

Question 29

Which of the following inhalation agents is said to have “single breath” induction?

Answer 29

Desflurane

Question 30

This inhalation agent does not require a precision vaporizer. Its’ use also can decrease the anesthetic setting of the primary inhalation agent (Second Gas Effect). It should never be used in a closed circuit, thoracic surgery or gastrointestinal surgery. What is this agent?

Answer 30

Nitrous Oxide