Homework 6

Question 1

An “upgraded” version of this drug has the preservative benzyl alcohol, which could be toxic to cats especially at high doses.

Answer 1

Propofol

Question 2

This macroemulsion milky appearing injectable contains egg lecithin, glycerin and soybean oil. It is thought to augment the action of GABA. The recommended shelf life, once a vial is opened, is 6 hours.

Answer 2

Propofol

Question 3

This injectable anesthetic agent can be used for sedation, induction and maintenance of anesthesia. It is NOT a DEA controlled substance and does NOT offer analgesia. It is a potent respiratory depressant and rapid injection or high doses can result in life threatening apnea.

Answer 3

Propofol

Question 4

The dose of this intravenous medication should be administered IV slowly over 1-2 minutes with ¼ the calculated dose administered over 30 seconds

Answer 4

Propofol

Question 5

Although this IV drug does cross the placenta, it causes very little neonatal respiratory depression, but if given too rapidly to cats can cause Red Blood Cell hemolysis.

Answer 5

Etomidate

Question 6

This injectable sedative-hypnotic imidazole has minimal cardiovascular and respiratory effects, and is thought to augment the action of GABA.

Answer 6

Etomidate

Question 7

This IV injectable drug is costly, painful upon injection, and causes nausea and vomiting.

Answer 7

Etomidate

Question 8

Constant Rate Infusion (CRI) is not recommended with the use of this IV medication since it depresses adrenal cortical function.

Answer 8

Etomidate

Question 9

This Controlled Substance, when administered IV, should have ¼ of the calculated dose administered every 15 seconds until the desired effect for endotracheal intubation can occur.

Answer 9

Alfaxalone

Question 10

This Schedule IV Controlled Substance, is a steroid molecule and is thought to augment the action of GABA.

Answer 10

Alfaxalone

Question 11

This injectable dissociative anesthetic produces good somatic analgesia by inhibiting the NMDA receptor. It is licensed for use in cats and nonhuman primates.

Answer 11

Ketamine

Question 12

This injectable dissociative anesthetic is commonly mixed with diazepam and administered IV. When this mixture is administered IV, intubation can occur.

Answer 12

Ketamine

Question 13

This injectable dissociative anesthetic is only administered to dogs through an IV route since an IM injection may cause seizure.

Answer 13

Ketamine

Question 14

This injectable dissociative anesthetic agent comes as a combination medication premixed with zolazepam. This combination reduces the risk of seizure and helps promote skeletal muscle relaxation.

Answer 14

Tiletamine

Question 15

This injectable dissociative anesthetic agent appears to have less pronounced apneustic breathing than another member of this group

Answer 15

Tiletamine

Question 16

Propofol enters the brain quickly because…

Answer 16

• the brain is part of the vessel-rich group of tissues.

- propofol is lipid soluble and its entry into the brain is enhanced by the high lipid content of the brain.

Question 17

What is the term for a breathing pattern in which there is a pause for several seconds at the end of the inspiratory phase, followed by a short, quick expiratory phase.

Answer 17

apneustic respiration

Question 18

The lowest tissue for redistribution (lowest blood flow) is…

Answer 18

fat

Question 19

This is the most commonly used inhalant agent in North America.

Answer 19

Isoflurane

Question 20

Has a usual maintenance vaporizer setting between 1.5% and 2.5%

Answer 20

isoflurane

Question 21

Has the highest percentage of metabolism by the liver

Answer 21

sevoflurane

Question 22

This halogenated organic compound is best suited to be used for mask or chamber anesthesia induction.

Answer 22

Sevoflurane

Question 23

Can react with exhausted carbon dioxide absorber granules and has the greatest tendency to produce carbon monoxide.

Answer 23

Desflurane

Question 24

This agent has the highest vaporizer setting and requires an electronic, heated vaporizer.

Answer 24

Desflurane

Question 25

Highest M.A.C

Answer 25

Nitrous Oxide

Question 26

Has the lowest percentage of metabolism by the liver

Answer 26

Nitrous Oxide

Question 27

The modern halogenated inhalation agents have a high vapor pressure. This means…

Answer 27

• They commonly are administered through a precision vaporizer.
• If their delivery is not controlled, they could reach a delivery percentage of greater than
• 30% which could prove fatal to patients.
• They easily evaporate from a liquid to a gas.

Question 28

The ability of an inhalation agent to pass through the alveoli of the lung to the blood stream is related to the…

Answer 28

• concentration gradient of the agent in the alveoli

- lipid solubility of the agent

Question 29

The lower the partition coefficient is for an anesthetic means that the agent is better at dissolving in alveolar gas. Therefore, those agents that have lower partition coefficients…

Answer 29

have a faster induction to maintenance anesthesia and a faster recovery.

Question 30

An inhalation anesthetic agent with a higher M.A.C. value will have…

Answer 30

a higher precision vaporizer setting for induction and maintenance