Quiz 1

Question 1

What is each cephalosporin generation best for

Answer 1

Generation 1: Gram POS

Generation 2: ANEROBES (***)

Generation 3: Gram NEG

Generation 4: Broadest, PSEUDOMONAS, resistant infections

Question 2

CEPHEM NUCLEUS: WTF does it mean, who has it

Answer 2

Cefotetan
Cefoxitan

Cephem nucleus —> better for ANEROBES

Question 3

What must you NEVER give IV due to it effecting the cardiac conduction system?

Answer 3

Procaine penicillin

Question 4

Which has restricted use in race horses due to being excitatory?

Answer 4

Procaine

Question 5

Which drug combines with Tacobactam 8:1 to treat resistant pseudomonas

Answer 5

Pipercillin

Question 6

Pseudomonas in exotics is treated with….

Answer 6

Ceftazidime

Question 7

Which 3rd gen Cefalosporin is routinely used for Gram pos infections

Answer 7

Ceftiofur

Question 8

What can cause anaphylaxis and CNS disorders in birds/reptiles

Answer 8

Procaine penicillin

Question 9

Which cephalosporin is good because of its extended half life

Answer 9

Cefovecin

Question 10

If you hear ‘repository prep’ you think…

Answer 10

Benzocaine

Question 11

Which two cephalosporins are good for renal compromised patients

Answer 11

Cefoperazone

Ceftriaxone

Question 12

What is the only class that disrupts cell membrane syntheisis

Answer 12

Polymixins

Question 13

What is added to feed in pigs/chickens to treat Clostridium

Answer 13

Bacitracin

Question 14

What can you add to zinc-bacitracin to get a broader gram neg susceptibilty

Answer 14

Cloxacillin benzathine

–> its has gram neg and bacitracin has gram pos

Question 15

Whats preferred to treat Rhodoccus equi in horses (2)

Answer 15

Clarithromycin

Erythromycin + Rifampin

Question 16

Whats preferred for Ehrlichosis in dogs

Answer 16

Enrofloxacin

Marbofloxacin

Question 17

T/F Fluoroquinolones target mammalian ribosomes

Answer 17

FALSE —> thats chloramphenicols (which is why they are banned in food animals)

Question 18

T/F Fluoroquinolones arent that susceptible to bacterial resistance

Answer 18

False, it develops rapidly

Question 19

Which drug is active against DNA gyrase (topoisomerase II) and Topoisomerase IV

Answer 19

Pradafloxacin (new gen fluoro)

Question 20

Ototoxicity is a common side effect with which class

Answer 20

Aminoglycosides

Question 21

What causes retinal degeneration in cats

Answer 21

Enrofloxacin

Question 22

Which Fluoro is useful in treating occular lesions

Answer 22

Pradofloxacin

Question 23

Which macrolide is useful in cattle and swine for resp infections and only requires one dose

Answer 23

Tulathromycin

Question 24

Which drug is glucoronide conjugate excreted by bile is hydrolyzed by intestinal flora into an active drug and recirculated?

Answer 24

Chloramphenicol

Question 25

Which is widely distributed and able to treat CNS infections and respiratory tract infections?

Answer 25

Chloramphenicol

Question 26

T/F Chloramphenicols are suitable for Pseudomonas

Answer 26

False

Question 27

Is tyrosine fatal to horses

Answer 27

Yes

Question 28

Macrolides cause severe runs in

Answer 28

calves, adult horses

Question 29

You hear Campylobacter jejuni in dogs, you think…..

Answer 29

ERYTHROMYCIN

Question 30

Two TYPE III (concentration + PAE) macrolides

Answer 30

Azithromycin

Tulathromycin

Question 31

Which drug class has a low incidence of toxicity

Answer 31

Macrolides

Question 32

When is it effective to give an IV of Tilmicosin?

Answer 32

NEVER — cardiotoxic

Can give SUB-CUT cows/pigs for resp pathogens

Question 33

Type of metabolism in macrolides

Answer 33

Little - Erythomycin is oxidated

Question 34

Lincamycin + Spectinomycin for….

Answer 34

Gram POS and NEG infection of pigs/poultry