Quiz 1 Flashcards
What is each cephalosporin generation best for
Generation 1: Gram POS
Generation 2: ANEROBES (***)
Generation 3: Gram NEG
Generation 4: Broadest, PSEUDOMONAS, resistant infections
CEPHEM NUCLEUS: WTF does it mean, who has it
Cefotetan
Cefoxitan
Cephem nucleus —> better for ANEROBES
What must you NEVER give IV due to it effecting the cardiac conduction system?
Procaine penicillin
Which has restricted use in race horses due to being excitatory?
Procaine
Which drug combines with Tacobactam 8:1 to treat resistant pseudomonas
Pipercillin
Pseudomonas in exotics is treated with….
Ceftazidime
Which 3rd gen Cefalosporin is routinely used for Gram pos infections
Ceftiofur
What can cause anaphylaxis and CNS disorders in birds/reptiles
Procaine penicillin
Which cephalosporin is good because of its extended half life
Cefovecin
If you hear ‘repository prep’ you think…
Benzocaine
Which two cephalosporins are good for renal compromised patients
Cefoperazone
Ceftriaxone
What is the only class that disrupts cell membrane syntheisis
Polymixins
What is added to feed in pigs/chickens to treat Clostridium
Bacitracin
What can you add to zinc-bacitracin to get a broader gram neg susceptibilty
Cloxacillin benzathine
–> its has gram neg and bacitracin has gram pos
Whats preferred to treat Rhodoccus equi in horses (2)
Clarithromycin
Erythromycin + Rifampin
Whats preferred for Ehrlichosis in dogs
Enrofloxacin
Marbofloxacin
T/F Fluoroquinolones target mammalian ribosomes
FALSE —> thats chloramphenicols (which is why they are banned in food animals)
T/F Fluoroquinolones arent that susceptible to bacterial resistance
False, it develops rapidly
Which drug is active against DNA gyrase (topoisomerase II) and Topoisomerase IV
Pradafloxacin (new gen fluoro)
Ototoxicity is a common side effect with which class
Aminoglycosides
What causes retinal degeneration in cats
Enrofloxacin
Which Fluoro is useful in treating occular lesions
Pradofloxacin
Which macrolide is useful in cattle and swine for resp infections and only requires one dose
Tulathromycin
Which drug is glucoronide conjugate excreted by bile is hydrolyzed by intestinal flora into an active drug and recirculated?
Chloramphenicol
Which is widely distributed and able to treat CNS infections and respiratory tract infections?
Chloramphenicol
T/F Chloramphenicols are suitable for Pseudomonas
False
Is tyrosine fatal to horses
Yes
Macrolides cause severe runs in
calves, adult horses
You hear Campylobacter jejuni in dogs, you think…..
ERYTHROMYCIN
Two TYPE III (concentration + PAE) macrolides
Azithromycin
Tulathromycin
Which drug class has a low incidence of toxicity
Macrolides
When is it effective to give an IV of Tilmicosin?
NEVER — cardiotoxic
Can give SUB-CUT cows/pigs for resp pathogens
Type of metabolism in macrolides
Little - Erythomycin is oxidated
Lincamycin + Spectinomycin for….
Gram POS and NEG infection of pigs/poultry
