Quaternary Struc Flashcards
What are the forces that stabilise interactions between proteins and protein subunits
Noncovalent interactions
Why do polypeptide chains associate?
To perform a variety of functions
How are Metabolic pathways organised?
By the association of a number of separate polypeptides
why are metabolic pathways organised the way they are
Allows efficient channelling of pathway intermediates from one enzyme to the next
Name some quaternary complexes
Collagen, DNA Pol3 holoenzyme of Ecoli, Ribsomal complexes
ATCase is an example of what
Allosteric regulation
what is allosteric regulation
regulation of a protein by binding an effector molecule at a site other than the protein’s active site
ATCase catalyzes a reaction in what
pyrimidines
What two things can bind to ATCase
ATP and CTP
ATCase activity is inhibited by what and activated by what
Inhib by CTP and Act by ATP so they compete for the same site on the same thing
Allosteric regulation involves what
Changes quarternary structure- rearrangement of subunits in T to R transition