Quaternary Struc Flashcards

1
Q

What are the forces that stabilise interactions between proteins and protein subunits

A

Noncovalent interactions

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2
Q

Why do polypeptide chains associate?

A

To perform a variety of functions

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3
Q

How are Metabolic pathways organised?

A

By the association of a number of separate polypeptides

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4
Q

why are metabolic pathways organised the way they are

A

Allows efficient channelling of pathway intermediates from one enzyme to the next

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5
Q

Name some quaternary complexes

A

Collagen, DNA Pol3 holoenzyme of Ecoli, Ribsomal complexes

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6
Q

ATCase is an example of what

A

Allosteric regulation

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7
Q

what is allosteric regulation

A

regulation of a protein by binding an effector molecule at a site other than the protein’s active site

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8
Q

ATCase catalyzes a reaction in what

A

pyrimidines

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9
Q

What two things can bind to ATCase

A

ATP and CTP

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10
Q

ATCase activity is inhibited by what and activated by what

A

Inhib by CTP and Act by ATP so they compete for the same site on the same thing

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11
Q

Allosteric regulation involves what

A

Changes quarternary structure- rearrangement of subunits in T to R transition

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