Globular proteins

Question 1

Difference between globular and fibrous

Answer 1

Globular are folded into compact structures

Question 2

Globular can contain what regions

Answer 2

locally folded regions of secondary structure as well as irregular folding

Question 3

What must be present to achieve a compact structure

Answer 3

Polypeptide chain must have loops/turns which link the secondary structural elements

Question 4

what turns play a role in compact structures

Answer 4

B and Y turns

Question 5

what amino acid generally plays a role in turns

Answer 5

proline

Question 6

Bends and turns are found where on the proteins

Answer 6

surface

Question 7

Many globular proteins have what type of coils

Answer 7

random

Question 8

What method has been used to confirm that each region has a particular fold

Answer 8

x ray diffraction

Question 9

random coil cannot be observed by

Answer 9

X ray diffraction

Question 10

Polar side chains are usually found where but where else can they be and why

Answer 10

Usually found near the outside or on the surface of the protein.
Can be buried inside the protein and usually H bonded to other side chains or peptide bonds

Question 11

globular proteins are somewhat soluble, true or false?

Answer 11

true