CO2 transport in Hemo

Question 1

Release of CO2 from respiring tissue lowers what

Answer 1

the O2 binding affinity of hemoglobin

Question 2

Some CO2 becomes what and contributes to what effect

Answer 2

Becomes bicarb by release H+ and contributes to Bohr effect

Question 3

Some bicarb reacts directly with what to form what

Answer 3

directly with hemoglobin to form carbamates

Question 4

what allows hemoglobin to transport Co2 from tissues to lungs

Answer 4

Carbamation

Question 5

A negatively charged group is introduced at what terminus

Answer 5

N terminus of the chains

Question 6

Negatively charged group introduced at N terminus stabilises what and what state is this

Answer 6

salt bridge between alpha and beta chains, characteristic of deoxyhb state

Question 7

What promotes release of O2 when CO2 is present in tissue

Answer 7

lowering of pH

Question 8

In the lungs where O2 is abundant, O2 binding favours what?

Answer 8

favours the oxyHb form and CO2 is released

Question 9

In tissues where CO2 is abundant, the pH is lowered by what and what form is favoured

Answer 9

Lowered by H+ and the deoxyHb is favoured promoting the release of O2