QTS cards - Psych Flashcards
methylphenidate
ADHD tx - stimulant
Inc catecholamines NE, DOPA in synaptic cleft
+appetite control (AE - dec appetite, weight loss)
Alcohol withdrawal tx
long-acting benzodiapines
Chlordiazepoxide
Lorazepam
Diazepam
Antipsychotic
Haloperidol + AZINES
block dopamine D2 receptors in nigrostrial pathway
INC cAMP
Antipsychotic AE
Haloperidol + AZINES
endocrine - INC prolactin (tuberoinfundibulnar pathway)
NMS - rigidity, HTN, HR inc, fever (tx dANTROle)
tardive dyskinesia - lip-smacking, choreoatheotoid movement (bc INC up regulation of dopa receptors)
Antipsychotic - EPS side effects
Haloperidol + AZINES
4 hr - acute dystonia (toticolis, eyes up-oculogyric crisis)
4 day - akathisia (fidgety/anxious)
4 wk - bradykinesia (parkinsonisms)
4 mo - tardive dyskinesia (lip smacking, chorea move)
Clozapine
tx resistant schizophrenia (+suicide)
AE:
INC weight (as olanzapine) - check metabolic panel
agranulocytosis - WBC check weekly
Risperidone AE
raspado con leche
schizophrenia tx
inhibit dopamine -> INC prolactin -> irregular menstruation, infertility
Lithium
LMNOP
bipolar
narrow therapeutic window
AE: movement tremor Nephrogenic DI (antagonist to ADH) hypOthyroidism Pregnancy problems
kidney excretion (bc hydrochlorothiazide, ACE inhibit, NSAIDS > INC toxicity)
buspirone
generalized anxiety dz
stimulate 5-HT
takes 1-2 weeks to take effect
SSRIs
FLUoxetine
PARoxetine
SERtraline
CITAlopram
block 5-HT reuptake
Depression, generalized anxiety disorder, panic disorder, OCD, bulimia, PTSD, social phobias
SSRIs AE
FLUoxetine
PARoxetine
SERtraline
CITAlopram
sexual dysfunction
serotonin syndrome - hyperthermia, confusion, myoclonus, flushing, diarrhea, seizures, hear instability
TX - cyproheptadine (5-HT receptor antagonist)
TCA AE
amityptyline
pramine
pine
a1 - block effects - postural hypotension
atropine like(anticholinergic) - hot, red, dry, blind, crazy
Convulsion, Coma, Cardiotoxic (arrhythmia bc block fast Na channel)
Inc AE in elderly - confusion, hallucinations
TX - NaHCO3
MAO inhibitors
Phenelzine
atypical depression (mood reactivity, Inc appetite/sleep)
AE - HTN crisis, CNS stimulation
washout period 2wks - after rx discontinue to allow resyntheiss of MAO (avoid serotonin syndrome)
BUpropion
#1 x major depression sz with NO sexual dysfunction ae INC NE/Dopa
AE - seizures in anorexic/bulimic bc lowers threshold
TrazoBONE AE
antidepressant
priapism (prolonged painful erection)