QTS cards - Reproductive Flashcards
Leuprolide
lieu of GnRH
pulsatile - agonist
continuous - antagonist
dec FSH/LH –> Dec testosterone/DHT
anastrozole
inhibits aromatase
no testosteron –> estradiol
Progestins
oral contraceptive
dec GnRH - NO ovulation, no FSH/LH
only progestin - Inc thickness mucus, impair sperm
mifePRISTone
competitive inhibitor of progestin
terminates pregnancy
oral contraceptive
CI in smokers (check smoking pts status prior)
CI in hypertriglycemia, liver dz, pregnancy
methyltestosterone
testosterone
anabolic steroid use in young athletes
DEC intratestituclar testosterone –> gonadal atrophy
acne
FIVEasteride
5a - reductase inhibitor
tx - BPH, male-pattern baldness
flutANide
non steroidal competitive inhibitor at androgen receptors
impaired androgen-receptor interaction
sildenafil
inhibits PDE5 (phosphodiesterase) inc cGMP (corpus cavernosum) INC blood blood
AE - HYPOTENSION (+nitrates pts)