Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Mercy CLS 2: Microbiology > QC, Disinfection, Sterilization > Flashcards

QC, Disinfection, Sterilization Flashcards

1
Q

IQCP

A

individualized quality control plan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

IQCP replaces…

A

EQC (equivalent quality control) - the standardized approach

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

IQCP is based on…

A
  • assessment of the unique laboratory testing in use
  • patient populations
  • other factors (ie. internal quality checks built into new instruments)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

IQCP is not required on —– tests

A

waived

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

3 parts of IQCP

A
  1. Risk assessment
  2. Quality control plan
  3. Quality control assessment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

5 things IDd in risk assessment phase of IQCP

A
  • how frequently they may occur
  • how likely it is they will be detected
  • potential severity for patient
  • risk prevention/mitigation
  • acceptability of residual risk
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

QCP must include…

A

numer, type and frequency of QC testing, and acceptable criteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

not eligible to use IQCP

A

pathology, histology, cytology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

IQCP may result in less stringent QC than the standardized method because…

A

it is risk-based

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

used to document elements of risk analysis

A

Failure Modes and Effects Analysis (FMEA) table

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

2 quality management tools focusing on the pre- and post-analytical phases

A

Q-probes
Q-tracks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

provides a series of cross-sectional quality assurance studies with peer evaluations

A

Q-probes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

provides continuous quality monitors for tracking changes over time

A

Q-tracks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

most variation and highest proportion of errors

A

preanalytical phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

average time to detect a persistent error

A

1/2 of the time between control analyses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

magnitude of total error that can be tolerated without invalidating the medical usefulness of the result

A

maximum allowable error (MAE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

control procedure that uses patient data

A

average of patient (AOP) data

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

usefulness of mercurials

A
  • toxic, not recommended
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

usefulness of quaternary ammonium compounds

A
  • active against bacteria, lipid viruses
  • inactive against spores
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

usefulness of phenolic compounds

A
  • active against bacteria, Mycobacterium, fungi, lipid viruses
  • less effective against spores
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

usefulness of chlorine compounds

A
  • active against bacteria, viruses, spores
  • corrosive to metals
  • must be made fresh
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

usefulness of iodophores

A
  • active against vegetative bacteria and viruses
  • not active against spores
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

usefulness of alcohols

A
  • general use disinfectant
  • not active against spores
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

usefulness of formaldehyde

A
  • active against bacteria, spores, viruses
  • irritating odor, carcinogenic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
usefulness of activated glutaraldehyde
- toxic, potential damage to eyes
25
usefulness of formaldehyde-alcohol
- active against bacteria, spores, viruses
26
agents useful against spores
- chlorine compounds - formaldehye solutions - formaldehyde-alcohol
27
methods of sterilization
- gas - dry heat - chemical - steam (autoclave) - filtration - radiation
28
used to sterilize items that are easily corroded, such as cutting instruments, and requires longer exposure time
dry heat sterilization
29
takes hours to sterilize; mainly used for wheelchairs and beds
gas sterilization
30
gases used for sterilization
- ethylene oxide - paraformaldehyde
31
used when a material cannot be autoclaved; uses the same agents as disinfection with longer exposure times
chemical sterilization
32
autoclave conditions
15 PSI (1 atm) 15 minutes 121° C
33
useful as a sterilization indicator
Bacillus or Geobacillus spores
34
most frequent reason for autoclave failing
lack of contact between steam and microorganisms
35
disinfection
a process that eliminates a defined scope of microbes, including some spores
36
antiseptics are applied to -------- and do not kill --------
the skin spores
37
factors that influence the degree of killing microbes
- types of organisms - number of organisms - concentration of disinfecting agent - presence of organic material - nature of surface - contact time - temp - pH - biofilms - compatibility of disinfectants and sterilants
38
why is steam sterilization effective?
heat in water is transferred more readily to a cool body than heat in air
39
commonly used to sterilize glassware and oils
dry heat
40
2 methods that achieve disinfection but not sterilization and do not eliminate spores
boiling pasteurization
41
pasteurization conditions
72° C 15 seconds
42
most microbes are retained by a pore size of...
0.45 - 0.80 um
43
pore size for critical sterilization
0.22 um Pseudomonas can pass through other pores
44
HEPA
high efficiency particulate air
45
HEPA is able to remove microbes larger than...
0.3 um
46
2 forms of radiation
ionizing (used to sterilize disposable supplies) nonionizing
47
all disinfectants regulated by... sterilizers regulated by...
EPA FDA
48
4 means by which chemical agents kill microbes
- react with components of membrane - denaturation of proteins - reaction with thiol (-SH) groups of enzymes - damage of DNA/RNA
49
denature proteins; make lipids soluble
alcohols
50
react with NH2, SH, and COOH groups
aldehydes
51
inactivate proteins
tincture of iodine
52
reacts with water to form HClO; oxidizer
chlorine
53
precipitates proteins
silver nitrate
54
reacts with -SH; lyses membranes
mercuric chloride
55
disrupts cell membranes
detergents (quaternary ammonium compounds)
56
aklylating agent
ethylene oxide
57
sterilize bio-hazardous waste
autoclave if heat stable
58
sterilize media, liquids, instruments
autoclave
59
sterilize disposable supplies
ionizing radiation
60
sterilize antibiotics, vaccines, carbohydrates
filtration
61
sterilize glassware, oil
dry heat
62
critical materials
invade sterile tissues or enter vascular system
63
semicritical materials
come into contact with mucous membranes
64
noncritical materials
come into contact with skin
65
autoclave factors that must be monitored
sterilization indicators culture tests time, pressure, temp

Mercy CLS 2: Microbiology (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions