Psychology and Sociology: Drugs Flashcards
Depressants
Reduce nervous system activity, resulting in a sense of relaxation and reduced anxiety
Alcohol (depressant)
-increase activity of the GABA receptor; leads to brain inhibition
-Disinhibition: a lack of self-control; occurs because the centers of the brain that prevent inappropriate behavior are depressed
-increase dopamine levels
-Logical reasoning and motor skills are affected, may experience fatigue
-Alcohol myopia: a short-sighted view of the world due to an inability to recognize consequences of actions
-Cirrhosis, liver failure, pancreatic damage, gastric or duodenal ulcers, gastrointestinal cancer, and brain disorders
-Wernicke-Korsakoff syndrome: caused by a deficiency of thiamine and characterized by severe memory impairment with changes in mental status and loss of motor skills
Sedatives
-Tend to depress central nervous system activity, resulting in feelings of calm, relaxation, and drowsiness
-Barbiturates: historically used as anxiety-reducing and sleep medications
-Benzodiazepines: less prone to overdose so have replaced barbiturates
-Increase GABA activity, causing sense of relaxation
-Highly addictive
Stimulants
Cause an increase in arousal in the nervous system
Amphetamines (stimulant)
-Cause increased arousal by increasing release of dopamine, norepinephrine, and serotonin at the synapse and decreasing their reuptake
-Increases arousal and causes a reduction in appetite and decreased need for sleep
-Increase in heart rate and blood pressure
-Euphoria, hypervigilance, anxiety, delusions of grandeur, and paranoia
Cocaine (stimulant)
Also acts on dopamine, norepinephrine, and serotonin shapes, but decreases reuptake of the neurotransmitters
Ecstasy (stimulant)
-Acts as a hallucinogen combined with an amphetamine
-Increased heart rate, increased blood pressure, blurry vision, sweating, nausea, and hyperthermia
-Feelings of euphoria, increased alertness, and an overwhelming sense of well-being and connectedness
Opiates and Opioids
-types of narcotics
-Opiates: naturally occurring forms
-Opioids: semisynthetic derivatives
-Compounds bind to opioid receptors in the peripheral and central nervous system
-Act as endorphin agonists and cause decreased reaction to pain and a sense of euphoria
-Ex: heroin, oxycodone, and hydrocodone
Hallucinogens
-Drugs that typically cause introspection, distortions of reality and fantasy, and enhancement of sensory experiences
-Increased heart rate and blood pressure, dilation of pupils, sweating, and increased body temperature
-Ex: lysergic acid diethylamide (LSD), mushrooms
Marijuana
-Active chemical: tetrahydrocannabinol (THC)
-THC acts at cannabinoid receptors, glycine receptors, and opioid receptors
-Inhibits GABA activity and indirectly increases dopamine activity
-Eye redness, dry mouth, fatigue, impairment of short-term memory, increased heart rate, increased appetite, lowered blood pressure
Drug addiction
-Highly related to the mesolimbic reward pathway, one of the four dopaminergic pathways in the brain
-Pathway includes the nucleus accumbens, ventral tegmental area, and the medial forebrain bundle
-This addiction pathway is activated by all substances that produce psychological dependence