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Pharmocology - step > Psychiatry > Flashcards

Psychiatry Flashcards

1
Q

DOC @ ADHD

A

stimulants

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2
Q

DOC @ OH withdrawal

A

long acting benzos

chlordiazeoxide, lorazepma, diazepam

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3
Q

DOC @ bipolar

A

litiuim, valproid acid, atypical antypsychotics ( olanzapine, clozapine, queitapine, risperidone, aripiprazole, ziprasidone)

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4
Q

DOC @ bulimia

A

SSRI ( fluoxetine, paroxetine, sertraline, citalopram)

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5
Q

DOC @ depression

A

SSRI (fluoxetine, paroxetine, sertraline, citalopram)

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6
Q

DOC @ GAD

A

SSRI (fluoxetine, paroxetine, sertraline, citalopram)
SNRI (venlafaxine, duloxetine)
busprion

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7
Q

DOC @ schizophrenia

A 
atypical antipsychotics (haloperidol, trifluoperazine, flupenazine, thioridazine, chlorpromazine)
-AZINES
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8
Q

DOC @ social phobias

A

SSRIs (fluoxetine, paroxetine, sertraline, citalopram)

beta blockers

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9
Q

DOC @ OCD

A

SSRIs (fluoxetine, paroxetine, sertraline, citalopram)

clomipramine (TCA)

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10
Q

DOC @ panic disorder

A

SSRI (fluoxetine, paroxetine, sertraline, citalopram)
venlafaxine (SNRI)
benzodiazepines

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11
Q

DOC @ PTSD

A

SSRI (fluoxetine, paroxetine, sertraline, citalopram)

venlafaxine (SNRI)

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12
Q

DOC @ Tourette syndrome

A

antipsychtics (fluphenazien, pimozide)

tertrabenazine

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13
Q

uses of methylphenidate, destroamphetamine methamphetamie

A

ADHD
narcolepsy
appetite stimulant

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14
Q

increased NE and DA especially used for ADHD

A

CNS stimulatns

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15
Q

increses NE and DA

A

CNS stimulants

buproprion

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16
Q

list the typicl antipsychotics

A 
haloperisol
trifluoperazine
fluphenazine
thioridazine
chlorpromazine
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17
Q

moa of typical antipsychotics

A

block D2 – increase cAMP

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18
Q

uses of typical antipsychotics

A

positive symptoms of schizophrena
psychosis
acute mania
Tourette syndrome

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19
Q

high potency typical antipsychotics please

A

haloperidol
trifluoperazine
fluphenazine
TRY to FLY High

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20
Q

low potency typical antipsychotics please

A

chlorpromazine

thioridazine

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21
Q

a/se of typical antipsychotics in general

A 
EPS
endocrine - hyperprolacti
anticholi - dry mouth, constipation
antiadrena1 - hypotension
antihista - sedation
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22
Q

what can cause QT prolongation

A

typical antipsychotics
atypical antipsychotics
TCAs

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23
Q

what s/e with haloperidol

A

EPS
Neurleptic malignant syndrome
tardive dyskinesia

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24
Q

what s/e with trifluoperazine and fluphenazine

A

eps - huntingot, delirium,

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25
what s/e with chlorpormazine
anti choli anti alpha 1 anti histamine corneal deposits
26
what s/e with thioridazine
anti choli anti alpha 1 anti histamine retinal deposits
27
rigidity Myoglobinuria autonomic instability hyperpyreia
neuroleptic malignany syndrome | haloperidol
28
how do you treat rigidity/Myoglobinuria/autonomic instability/hyperpyrexia with haloperid use
dantrolene | D2 agonists - bromocriptin
29
descrien the evolution of EPS sides efects
4 hours acute dystonia (muscle spasm, stiffness, oculogyric crisis) 4 day akathisia/restlessness 4 week bradykinesia/parkinsonism 4 month tardive dyskinesia
30
symptoms of neuroleptic malignancy syndrome
``` ridigity, Myoglobinuria, autonomic instability, hyperpyrexia treat with dantrolene and D2 agonist ie bromocription FEVER fever encephalopathy vitals unstable enzymes increase d(muscle) rigidity of muscles ```
31
how do you treat the extrapyramidal system side effects of high potentncy typical antipsychotis
haloperidol, trifluoperazine, fluphenazie | BENZTROPINE and DIPHENHYDRAMIE
32
used of benztropine and diphenhydramine
eps symptoms of high potency typical antipsychotics
33
list the atypical antipsychotics please
olanzapine, clozapine, quetiapine resperidone aripiprazole, ziprasidone
34
MOA of atypical antipsychotics please
not completely udnerstonnd | varied at 5HT2, dopamine, H1 and Ne receptors
35
use of atypical antipsychotics please
``` positive and negative schizophrenia bipolar OCD anxiety tourettes depression mania ```
36
how do s/e between typical and atypical antipsychotics vary
less eps and anticholis in atypical
37
s/ae of clozapine please
AGRANULOCYTOSIS, weight gain, seizure
38
a/se of olanzapine please
weight gain
39
a/se of resiperidone
increased prolactin lactatin, gynecomastia irregular menstratuion fertility issues
40
a/se of all atypical antipscyhotics
QT prolongation
41
what is moa of lithium
not really known | inhibit of phosphoinositol cascaise
42
use of lithium
SIADH (wherease SSRi cause) mood stabilized for bipolar blocks relapse and acute main
43
a/se of lithium
``` tremor hypothyroidism ebstein anomaly in pregos nephrogenic diabetes insipidius kidney ```
44
what do you use in lithium toxocity
thiazides
45
moa of busprion
stimulats 5HT1a
46
use of busprion
GAD (alsoSSRi and SNRI)
47
benefits of busprion
no addiction, tolerance, sedation | no interaction with OH (barbiturates and benzos do)
48
list the SSRIs please
fluoxetine paroxetine sertraline citalopram
49
MOA of SSRIs please
5ht reuptake inhibitors
50
used of SSRI
``` depression GAD panic disorder OCD bulimia social phobias PTSD ```
51
a/se of SSRI
``` serotonin syndrome (Ssri, snri, tca, maoi, meeperidine, ) gi distress sexual dysfunction - anorgasmia, decreased libido ```
52
``` hyperthermia confusion myoclonus cardiovascular instability flushing diarrhoea seizures ```
serotonin syndrome
53
how to treat serotonin syndrome
cyproheptadine a 5HT2 antag
54
sxs fo serotonin syndrome
``` hyperthermia confusion myoclonus cardiovascular instability flushing diarrhoea seizures ```
55
lsit the snris please
venlafaxine, duloxetine
56
diabetic peripheral neupahty
duloxetine
57
moa of snris
inhibit Ne and 5Ht reuptake
58
ase of SNRIs
increased bp most common stimulant effects sedation nausea
59
useds of venlafaxine
depression, GAD, panic disorder, PTSD
60
list the tcas please
amitriptyline, nortriptyline imipramine, desipramiine, clomipramine doxepin, amoxapine
61
moa of tca
block reuptae of Ne and 5ht
62
uses of tca
``` major depression ocd - clomipramine peripheral neuropathy chronic pain migraine prophylaxis ```
63
migraine prophylaxis
tcas
64
chronic pain
tcas
65
a/se of tcas
anti alpha 1 anti chloi prolongation of qt itnerval
66
tca to use in elderly and why
nortriptyline bc less anticholis that would cause confusion and halluciations
67
how to prevent arrhythmia with tca use
naHCo3
68
serious a/se of tcas
coma convulsions cardiotoxicity resp depression
69
NaHCO3
prevent arrhythmias in TCAs
70
list the MAOis please
``` MAO takes pride in changhai tranylcypromine phenelzine isocarboxazid selegiline ```
71
how is selegiline diff
selevite MAO B inhibitor
72
what is the moa of maois?
nonselectie MAO inhibition increases amine NT ie Ne, 5Ht, and Da
73
uses of MAOis
atypical depression | anxiety
74
a/se of maois
hypertensive crisis with tyramine | CNS stimulation
75
contraindicated at maois
cheese and wine - hypertensive crisis | serotonin syndrome - ssri, tca, st johsn wart, meperidine, dextromethorphan
76
use of buproprion
smoking cessation
77
moa of buproprion
increase ne and da with unknown moa
78
a/se of buproprion
stimulatnt - tach and insomnia headache seizures in anorexic/bulimic patients
79
what is buproprion godo for
no sexy time effects
80
moa of mirtazapine
inhibits alpha 2 -- increase Ne and 5HT release | 5Ht2 and 5HT3 inhibitiors
81
uses of miertazapine
depression - want to sleep bc causes sedation | weight gain in elderly or anorexix (also causes increased appetite)
82
a/se fo miertazapine
sedation weight gain increased appetite dry mouth
83
what is trazodone known for
priapism
84
moa of trazodone
blocsk 5HT2 and alpha 1
85
what is trazodone used for
insomina
86
a/se of trazodone
priapism sedation nausea postural hypotension

Pharmocology - step (16 decks)

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