CYP450s inhibitors, inducers and sulfas Flashcards

1
Q

AAA RACKS IN GQ M

CCGPPRNSN

A

yep

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2
Q

acute alcohol abuse

A

inhibitor

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3
Q

chronic alcohol abuse

A

inducer

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4
Q

ritonavir

A

inhibitor

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5
Q

amiodarone

A

inhibitor

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6
Q

cimetidine

A

inhibitor

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7
Q

ketoconazole

A

inhibitor

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8
Q

sulfonamides

A

inhibitor

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9
Q

isoniazid

A

inhibitor

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10
Q

grapefruit juice

A

inhibitor

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11
Q

quinidine

A

inhibitor

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12
Q

macrolides

A

inhibitor

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13
Q

st johns wort

A

inducer

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14
Q

phenytoin

A

inducer

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15
Q

phenobarbital

A

inducer

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16
Q

nevirapine

A

inducer

17
Q

rifampin

A

inducer

18
Q

griseofulvin

A

inducer

19
Q

carbamazepine

A

inducer

20
Q

list all inhibitors

A

acute alcohol abuse, ritonavir, amiodarone, cimetidine, ketoconazole, sulfomamides, isoniazid, grapefruit guice, quinidine, macrolides

21
Q

list all inducers

A

chonic alchol abuse, ste johns ort, phenytoin, phenobarbital, nevirapine, rifampin, grisefulvin, carbamazepine

22
Q

list all substrates

A

A TWO

antipsychotics, theophylline, warfarin, OCP

23
Q

antipsychotics

A

substrat

24
Q

theophylline

A

substrate

25
Q

warfarin

A

substrate

26
Q

OCP

A

substrate

27
Q

list all the sulfa drugs

A

PFACTSSS: probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamide antibiotics, sulfasalazine, sulfonylureas

28
Q

probenecid

A

sulfa drug

29
Q

furosemide

A

sulf drug

30
Q

acetazolamide

A

sulfa drug

31
Q

celecoxib

A

sulfa drug

32
Q

thiazides

A

sulfa drug

33
Q

sulfonamide antibiotics

A

sulfa drug

34
Q

sulfasalazine

A

sulfa drug

35
Q

sulfonylureas

A

sulfa drug