protozoa Flashcards

1
Q

what are protozoa?

A

“One celled animals”

Single cell with nucleus
(Eukarytoic)

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2
Q

what is the main biological role of protozoa?

A

:consumers of bacteria, algae, microfungi

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3
Q

how do protozoa function?

A

All engulf food by phagocytosis and then digest it in intracellular

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4
Q

what are the 5 major groups of protozoa?

A

Flagellates
Amoebae
Sporozoans
Ciliates
Microsporidia

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5
Q

describe flagellates

A

Flagellum as main locomotory organelle
Intestinal flagellates or other body sites

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6
Q

how do flagellates reproduce?

A

by binary fission

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7
Q

describe symptoms of African trypanosomiasis?

A

Fly like symptoms occur first, followed by the symptoms of CNS involvement such as personality change, alteration of the biological clock ie sleeping during the day and awake all night, confusion, speech disturbance, seizures, difficulty walking. Ultimately leading to death if untreated (either by neglect, coma, aspiration, seizures or cardiac arrhythmia/failure).

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8
Q

what is leishmaniasis disease?

A

disease that causes a range of clinical pictures as there are many species that affect humans.

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9
Q

how is leishmaniasis acquired?

A

It is acquired through the bite of an infected sandfly. Promastigotes from sandfly in picture

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10
Q

how is leishmaniasis diagnosed

A

Leish in humans is diagnosed through biopsy (amastigotes seen) or by serology combined with clinical signs.

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11
Q

how do Amoeba move?

A

Move by means of flowing cytoplasm and production of pseudopodia

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12
Q

Describe sporozoans- malaria?

A

No locomotory extensions
All species parasitic
Most intracellular parasites

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13
Q

how sporozoans- malaria reproduce?

A

Reproduce by multiple fission

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14
Q

what are ciliates?

A

Cilia that beat rhythmically at some stage in lifecycle

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15
Q

what are the two types of nuclei in ciliates?

A

2 types of nuclei – macro/micronucleus

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16
Q

what is microsporidia the product of?

A

Production of resistant spores

17
Q

describe microsporidia

A

Unique polar filament; coiled inside spore
Little known about human disease

18
Q

what is malaria?

A

Protozoan infection caused by Plasmodia sporozoan.

19
Q

what are the 5 species that cause human disease- malaria?

A

P.falciparum/orale/vivax/malariae/knowlesi

20
Q

how is malaria spread?

A

Transmitted by bite of female Anopheles mosquitoes

21
Q

life span of malaria

A

3-4 weeks

22
Q

how is malaria acquired

A

Infection acquired during feeding from infected human

23
Q

how long are you infected for w malaria?

A

Infected for life

24
Q

describe the malaria lifecycle

A

Liver stage in P.ovale and P.vivax has additional hypnozoite stage
Lie dormant and cause late relapse by reactivating months later
Not eradicated by most conventional anti-malarial treatments

25
Q

symptomatic malaria :

A

: fever, haemolysis

26
Q

what are clinical features of malaria?

A

Very varied
Fever almost invariable
Other common;
Chills and sweats
Headache
Myalgia
Fatigue
Nausea and vomiting
Diarrhoea
These acute symptoms common to all 4 species