Proteins Flashcards

1
Q

What are the 2 stages of protein synthesis?

A

Transcription and Translation

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2
Q

What is transcription in protein synthesis?

A

The transfer of genetic instructions in DNA to mRNA in the nucleus

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3
Q

What is translation in protein synthesis?

A

The process in which the genetic code in mRNA is read to make a protein at the ribosome.

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4
Q

What are codons?

A

The 3 letter sections of mRNA which code for blocks of proteins called AMINO ACIDS

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5
Q

How many amino acids are there?

A

20

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6
Q

Amino acids have a central carbon atom surrounded by which 3 things?

A

An amino group

A carboxyl group

A variable group (the R group)

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7
Q

What are the monomers of proteins?

A

the Amino Acids

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8
Q

Amino acids join together to form a polymer called a ____________

A

polypeptide (or a protein)

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9
Q

A condensation reaction is also called a _________

A

Dehydration reaction

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10
Q

two amino acids join together by forming a __________ bond

A

peptide

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11
Q

What is a polypeptide?

A

It can be a few amino acids bonded together or it can be thousands.

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12
Q

What are complex proteins?

A

Multiple polypeptide chains that are twisted and tangled together.

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13
Q

What is the primary structure of a protein?

A

It is the basic amino acid sequence

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14
Q

What are the secondary structures of proteins?

A

The secondary structure occurs when hydrogen bonds between nearby amino acids form creating structures called beta-pleated sheets and alpha helixes.

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15
Q

Beta pleated sheets are found in the protein (silk) that spiders use to make their webs

A
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16
Q

Alpha helix shape can be found in keratin (the protein found in our hair and finger nails)

A
17
Q

What are the tertiary structures of proteins?

A

The further folding together of polypeptide. It’s held together by interactions between the R-Groups of the amino acids.

It is still one single consistent strand of amino acids.

18
Q

What are quarternary structures of proteins?

A

This is when more than 1 polypeptide strand with tertiary structure is folded and tangled together.

19
Q

What types of bonds hold protein structures together?

A

Hydrogen Bonds

Ionic Bonds

Covalent Bonds

Disulphide Bridges
(only if the R-groups contain sulphur)

20
Q

What are the proteins with almost exclusively primary and secondary structures only?

A

Keratin and Silk (spider web)

21
Q

What are globular proteins?

A

The proteins of tertiary and quarternary structures that have folded into round/globe shapes

22
Q

What type of protein is hemoglobin?

A

a protein made of 4 separate peptide units in a quaternary structure

23
Q

What is denaturation?

A

When a protein loses its normal shape or configuration.

24
Q

What conditions cause denaturation?

A

Excessive Heat

Extremes of pH

Heavy Metal Exposure

25
Q

Example of Extreme Temperature in Denaturation

A

Curling Hair

Hair is composed of keratin (secondary structure - alpha helixes that are held together by weak hydrogen bonds)

Wash hair - Water (polar) affects the hydrogen bonds - changes the shape of hair when wet

26
Q

Example of extreme temperature denaturation

A

Curly hair

The polypeptide chains in hair twist together to form microfibrils that are held together by strong disulfide bridges.

Extreme Heat (and/or pH) can affect the strong disulfide bridges (breaking them and realigning them) resulting in denaturation.

27
Q

What is the structure of collagen?

A

Collagen triple helix

3 polypeptide chains that are twisted into fibers that are held together by hydrogen bonds

28
Q

Where can you find Collagen in your body?

A

The most common protein in your body

found in bones & cartilage

29
Q

What is the enzyme Bromelain?

A

Found in pineapple

Used to relieve sinus problems, reduce inflammation, and improve digestion.

Breaks down proteins

Prevents jello from setting