Blood - Notes Flashcards
What 2 components make up blood?
Plasma - 55%
Formed Elements - 45%
What are the major components of plasma?
Water
Plasma Proteins
Nutrients
Wastes
What is the function of Water in the plasma?
Maintains blood volume (+blood pressure)
Transports nutrients and wastes - water is a good solvent. Nutrients and wastes dissolve in it easily
Where is the major source of water in the plasma?
Absorbed into the blood from the colon
What is the function of the plasma proteins in the plasma?
Blood clotting proteins
Antibodies to fight infection
Hormones - chemical messengers
All proteins help maintain osmotic pressure
Where is the major source of plasma proteins?
Blood clotting proteins - Produced in the liver
Antibodies - Produced by white blood cells called lymphocytes
Hormones - Produced by endocrine glands
What is the function of the nutrients in the plasma?
Glucose, amino acids, vitamins, and minerals
Salts - Help maintain osmotic pressure
Where do nutrients in the plasma come from?
Absorbed into the blood through villi in small intestines.
What is the function of the wastes in the plasma?
CO2 - end product of metabolism (dissolved in plasma)
NH3 = ammonia
Urea - (NH3 + CO2 -> Urea)
Where do wastes in the plasma come from?
CO2 - Internal respiration at the tissues
NH3 - Deamination of amino acids
Urea - Produced in the liver
What are the formed elements of blood?
red blood cells
white blood cells
blood platelets
Where do the formed elements fo blood come from?
All made in the red bone marrow from stem cells
What are red blood cells?
Small biconcave, disc-shaped cells
no nuclei, contain hemoglobin
made in red bone marrow
live about 120 days, destroyed by liver and spleen
carry O2, bound to Hb (HbO2)
carry small amounts of CO2 bound to Hb (HbCO2)
act as a buffer by removing H+ ions from blood (HHb)
What is Hemoglobin?
a quarternary protein found in red blood cells
Hb + O2 -> HbO2 (oxyhemoglobin)
Hb + CO2 -> HbCO2 (carbaminohemoglobin)
Hb + H+ -> HHb (reduced hemoglobin)
Heme groups contain iron (Fe)
What are platelets?
fragments of cells
needed in blood clotting - form a temporary plug to stop bleeding
work together with blood clotting proteins (fibrin) to clot blood
produced in bone marrow