PROTEINS Flashcards
what are proteins
diverse group of large and complex polymer molecules, made of long chains of amino acids
what are amino acids
basic monomer units which combine to form a polymer called polypeptide, which can be combined to form proteins
role of proteins
structural-proteins are the main component of body tissues, such as muscle, skin, ligaments and hair
catalytic- all enzyme are proteins catalyzing many biochemical reactions
signaling-many hormones ad receptors are proteins
immunological-all antibodies are proteins
how many naturally occuring amino acids are there
20
formation of a peptide bond
Amino acid monomers combine to form a dipeptide, containing a peptide bond, by a condensation reaction
how is a polypeptide formed
The –OH group from one of the amino acids combine with the –H from amino group of the other amino acid
describe the primary structure of a protein
sequence of amino acids within proteins
the sequence is determined through an organisms DNA
determines the ultimate shape and therefore function of a protein
a change in a single amino acid can change the shape of the protein and stop it from functioning
describe the secondary structure of proteins
hydrogen on the -NH has a positive charge, while the Oxygen in -C=O has a negative charge
these two groups form weak bonds called hydrogen bonds
this causes the chain to be twisted into an alpha helix, creating a 3D shape
describe the tertiary structure of proteins
alpha helix can be twisted and folded even further to give the complex 3D structure of each protein
maintained by a different number of bonds:
disulfide bonds-fairly strong and only occur if the protein has amino acids containing sulphur
ionic bonds- formed between carboxyl and amino group which are easily broken
hydrogen bonds- numerous but easily broken
describe the quaternary structure of proteins
large and complex molecule
contains a number of individual polypeptide chains that are linked in various ways
may also be a non-protein group associated with the molecule, which helps with its function
e.g. hemoglobin contains an iron-containing haem group