Protein Trafficking Flashcards by Lindsay Kirkpatrick | Brainscape

Q

Free ribosomes synthesize

A

peripheral membrane proteins
cytosolic proteins
some proteins destined for nucleus, mitochondria & peroxisomes

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Q

RER synthesize

A

membrane bound proteins & secretory proteins
proteins in lysosomes, golgi & nuclear membrane

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Q

formation of RER

Signal sequence

A

First 20-30 amino acids which tell the ribosome to attach to the endoplasmic reticulum

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Q

formation of RER

Signal recognition particle (SRP)

A

Binds to the signal & the ribosome, then binds to the SRP receptor in the ER

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Q

formation of RER

SRP receptor

A

Located in the ER
allows protein to be inserted into lumen of ER creating RER

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