Neurotransmitters & Precursors Flashcards
phenylalanine
reaction
Phe -> Tyr
phenylalanine
enzyme
phenylalanine hydroxylase
what is NutraSweet and what does it interfere with?
D/L phenylalanine + aspartate (aspartame)
interferes with phenylalanine hydroxylase
tyrosine
catacholamines
Tyrosine->
- L Dopa
- Dopamine
- Norepinephrine
- Epinephrine
tyrosine
pigmentation
tyrosine -> melanin
enzyme = tyrosinase
what is missing in albinism?
melanin (have melanocytes)
tyrosine
thyroid hormones
- inactive: T4 (thyroxine)
- active: T3 (triiodothyronine)
T4 location
thyroid
T3 location
liver
T4 composition
2 tyr + 4 iodine
T3 composition
2 tyr + 3 iodine
how do T3 & T4 control metabolism?
make bigger and more mitochondria
tryptophan
products
serotonin
melatonin
niacin (B3)
tryptophan
serotonin reaction
Trp -> 5OHTrp -> 5HTP (5 hydroxytryptamine)
high levels of serotinin will cause…
increased bowel motility (diarrhea) + panic