Glycosaminoglycans Flashcards

1
Q

What complex carbohydrate is found in cell junctions?

A

Glycosaminoglycans

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2
Q

Name the 2 amino sugars

A

N-acetyl glucosamine (GlcNAc)
N-acetyl galactosamine (GalNAc)

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3
Q

What is the appearance of proteoglycans?

A

Bottle brush appearance

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4
Q

What is the general structure of glycosaminoglycans?

A

A hexosamine and a uronic acid residue

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5
Q

Name the 6 proteoglycans (GAG)

A

Hyaluronic acid
Chondroitin sulfate
Dermatan sulfate
Heparan sulfate
Heparin
Keratan sulfate

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6
Q

Hyaluronic acid amino sugar

A

Glucosamine

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7
Q

Hyaluronic acid location

A

Joint and ocular fluids

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8
Q

Chondroitin sulfate amino sugar

A

Galactosamine

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9
Q

Chondroitin sulfate location

A

Cartilage, tendons, bone

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10
Q

Dermatan sulfate amino sugar

A

Galactosamine

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11
Q

Dermatan sulfate location

A

Skin, valves, blood vessels

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12
Q

Heparan sulfate amino sugar

A

Glucosamine

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13
Q

Heparan sulfate location

A

Cell surfaces

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14
Q

Heparin amino sugar

A

Glucosamine

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15
Q

Heparin location

A

Mast cells, liver

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16
Q

Karatan sulfate amino sugar

A

Glucosamine

17
Q

Keratan sulfate location

A

Cartilage, cornea

18
Q

Which proteoglycans consist of the amino sugar galactosamine?

A

Chondroitin sulfate
Dermatan sulfate

19
Q

Which proteoglycans consist of the amino sugar glucosamine?

A

Hyaluronic acid
Heparan sulfate
Heparin
Keratan sulfate