Glycosaminoglycans Flashcards
What complex carbohydrate is found in cell junctions?
Glycosaminoglycans
Name the 2 amino sugars
N-acetyl glucosamine (GlcNAc)
N-acetyl galactosamine (GalNAc)
What is the appearance of proteoglycans?
Bottle brush appearance
What is the general structure of glycosaminoglycans?
A hexosamine and a uronic acid residue
Name the 6 proteoglycans (GAG)
Hyaluronic acid
Chondroitin sulfate
Dermatan sulfate
Heparan sulfate
Heparin
Keratan sulfate
Hyaluronic acid amino sugar
Glucosamine
Hyaluronic acid location
Joint and ocular fluids
Chondroitin sulfate amino sugar
Galactosamine
Chondroitin sulfate location
Cartilage, tendons, bone
Dermatan sulfate amino sugar
Galactosamine
Dermatan sulfate location
Skin, valves, blood vessels
Heparan sulfate amino sugar
Glucosamine
Heparan sulfate location
Cell surfaces
Heparin amino sugar
Glucosamine
Heparin location
Mast cells, liver