protein synthesis Flashcards
what is protein synthesis
the process of making proteins via transcription and translations- DNA codes for proteins but molecules are too large to exit nuclear envolope therefor they must by transcribed to enter cytoplasm and then sythensised in ribsosomes
Transcription
DNA strand serves as a template for mRNA to be fored via complementry nucleotide pairs, then nucleotides are joined via the enzyme RNA polymerase to form mRNA, then this is synthesised to remove introns and then exon chains are small enough to exit nuclear envolope
nucleotide pairs forming mRNA
cytosineguanine
adenine-> uracil
codons
sequences of 3 nucleotides which code for 1 AA, there is special ‘start’ and ‘stop’ codons which instruct the beginning and end of polymer chain
start & stop codons
start= AUG stop= UAA, UGA, UAG
translation
mRNA binds to ribosome where it binds to complemetry tRNA with each tRNA binded to a AA forming AA chain
translation nucleotide pairs
cytosine-> guanine
guanine-> cytosine
uracil-> adenine
what are polyribosomes
the cluster of AAs attached to the same mRNA strand
what is post-translational processing
when proteins are modified following translation
overview of protein synthesis
DNA to mRNA via transcription and splicing, mRNA exits nuclear envlope into cytoplasm, mRNA enters ribosome, in ribosome mRNA codes for tRNA molecules which has AAs attached, AAs form chains via polypeptide bonds which are proteins!