Endocrine system Flashcards
how it works
the excretion of hormones (chemical messages) from glands into BS for transportation to targeted tissues (effectors) which have complementary receptors to form a binding complex
what cells are exposed to hormones?
ALL cells are exposed to hormones as they are transported in the BS
but only complementry cells have the necessary receptors to react
in comparison the the nervous system, endocrine messages are….
slower + longer in duration
function (1) + how (5)
MAINTAIN HOMEOSTATSIS via:
- Regulate metabolic processes
- regulate water + electrolyte balances
- aid in transportation of substances across cell membranes
- control rate of chemical reactions
- role in reproduction, growth + dev.
what does the endocrine system control-> but not key functions (10)
- Metabolism
- Food digestion + intake
- tissue development
- ion levels
- water balance
- heart rate + BP
- glucose + nurient levels in blood
- reproductive functions + milk production
- urine production
- immune response
structure of hormones
an aqueous substance- must be water soubable to be transported around the blood: some are naturally water soulable some are lipid soluable therefore they require chaparone proteins
characteristics of water-soluable hormones (5)
- dissolve in plasma
- ‘free’ hormones as do not require protein to bind to for transportation
- relatively large in size
- do not easily diffuse through cell-membranes therefore require receptor to diffuse into cells (receptors external)
- short life-span: are rapidly broken down by hydrolytic enzymes
characteristics of lipid-soluable hormones (5)
- low-soluablity in aqueous fluids
- require chaperone proteins to allow transport through BS
- longer-lifespan (due to presentence of chaparone proteins)
- relatively small in size
- pass through lipid-cell-membranes and find receprtors internally
hormone life-span
variable as it depends on enzymes present in blood. measured via half-life
half-life of hormones
the time taken for 50% of the circulating hormone to be removed from the blood