Protein and fat digestion

Question 1

What do chief cells produce

Answer 1

Pepsinogen

Question 2

What triggers pepsinogen to be converted to pepsin

Answer 2

HCl

Question 3

What causes/releases gastrin

Answer 3

Vasovagal reflex and endocrine release

Question 4

What stimulates pepsinogen secretion

Answer 4

Gastrin

Question 5

Pancreatic proteases examples

Answer 5

Trypsin & chymotrypsin

Question 6

How are pancreatic proteases synthesised and packaged

Answer 6

Within secretory vesicles as inactive proenzymes - vesicles contain a trypsin inhibitor

Question 7

What activates pancreatic proteases

Answer 7

Enterokinase - secreted by mucosal membrane

Question 8

What transporter do di and tri peptides use

Answer 8

Human peptide transporter 1 to enter enterocyte

Question 9

What pumps are required for amino acids to enter blood vessel by facilitated diffusion

Answer 9

Na+/K+ ATPase and Na+/H+ exchanger 3

Question 10

What is secreted by gastric cells (gastric …)

Answer 10

Gastric lipase

Question 11

Where is gastric lipase secreted into in the stomach

Answer 11

Fundica mucosa

Question 12

What is not required for fat digestion in the stomach

Answer 12

Coliapse and bile acids

Question 13

Examples of bile acids

Answer 13

colic and chenodeoxycholic acid

Amphipathic

Question 14

What is pancreatic lipase secreted with in small intestine

Answer 14

Pro-colipase

Question 15

What is pro-colipase activated by/where

Answer 15

By trypsin in lumen

Question 16

Function of colipase

Answer 16

Stabilises pancreatic lipase and increases its efficiency

Question 17

Function of pancreatic lipase

Answer 17

hydrolyses TGs to glycerol and fatty acids

Question 18

Where and how do mono glycerol and fatty acids cross when being absorbed

Answer 18

Apical membrane of microvillus

Passive diffusion and lipid protein transporter mechanisms