Nutrient metabolism Flashcards

1
Q

Disease associated with Mal-digestion

A

Chronic pancreatitis
CF
Pancreatic carcinoma

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2
Q

Inadequate absorptive surface

A

Intestinal resection
Gastro colic fistula
Jejuno-ileal bypass

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3
Q

Bile salt deficiency

A
Cirrhosis
Cholestasis
Bacterial overgrowth
Impaired ileal reabsorption
Bile salt binders
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4
Q

Lymphatic obstruction

A

Lymphoma
Whipple’s disease
Intestinal lymphangiectasia

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5
Q

Vascular disease

A

Constructive pericarditis
Right sided HF
mesenteric arterial or venous insufficiency

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6
Q

Mucosal disease

A
Infection
Inflammatory diseases
Radiation enteritis
Eosinophilic enteritis
Ulcerative jejunitis
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7
Q

Cytokines in diseases with inflammatory responses

A

TNF-alpha - insulin resistance, glycolysis
IL2 - glucose metabolism
IL4 - glucose and lipid metabolism
IL6 - lipolysis

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8
Q

What does critical acute illness cause

A

Increase in synthesis of growth hormone
Anti-insulin effects
Anti-anabolic effects

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9
Q

Clinical manifestations of growth hormone increase

A

Hperglycaemia, hyperlipidaemia, hypercatabolic state, muscle wasting

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