Prostate Colloquia Flashcards
prostatic fluid does what?
break down viscous semen to aid in fertilization
most significant risk factor for prostate Ca?
age
Afro-american
FHx (1st degree relatives)
FHx of breast cancer as well (BRCA1 + 2)
If you have high PSA, how to interpret with more tests?
Free to total ratio
If low ratio: cancer
if high ratio: not cancer
Prostate Health Index: Pro2 PSA
Trend of increasing
risks for trans-rectal biopsy?
sepsis, gram -ve
active surveillance means what?
Sees them regularly with intent to cure
avoid overtreatment
watchful waiting is what?
watch the patient but with non-curative intent
PSA goes up for what?
Prostate Cancer
BPH
prostatitis
infection
Gleason Score explain:
architectural for the glands
2 numbers:
1-5 for most common cells
1-5 for second more common cells
Gleason score starts where?
6 out of 10
what’s an important PSA trend to consider?
PSA doubling time
what is ADT? when do you do it?
androgen deprivation therapy
post-intervention usually
ADT side effects?
cognitive change cardio vascular disease - hypercholeserolemia, IHD obesity osteoporosis (DEXA) lethargy, reduction in libido
hot flushes
when use chemo in prostate metastatic disease?
in conjunction with ADT
prostate accessible how?
perineal
rectum
